(2S)-1-(Diphenylphosphino)-3-phenyl-2-propanamine | CAS No. 146476-38-2
(2S)-1-(Diphenylphosphino)-3-phenyl-2-propanamine
Basic Information
CAS Number
146476-38-2
Molecular Formula
C21H22NP
Molecular Weight
319.39 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- (S)-1-(diphenylphosphino)-3-phenylpropan-2-aMine
- (αS)-α-[(Diphenylphosphino)methyl]benzeneethanamine
- [(2S)-2-Amino-3-phenylpropyl]diphenylphosphine
- (2S)-1-diphenylphosphanyl-3-phenylpropan-2-amine
- (alphaS)-alpha-[(Diphenylphosphino)methyl]benzeneethanamine
- (
- AS)-
- A-[(Diphenylphosphino)methyl]benzeneethanamine
- (S)-1-(Diphenylphosphanyl)-3-phenylpropan-2-amine
- Benzeneethanamine, α-[(diphenylphosphino)methyl]-, (αS)-
FAQ
What are the physical and chemical properties of (2S)-1-(Diphenylphosphino)-3-phenyl-2-propanamine (CAS: 146476-38-2)?
The compound (2S)-1-(Diphenylphosphino)-3-phenyl-2-propanamine (CAS: 146476-38-2) is a clear to slightly yellow liquid at room temperature. It has a molecular weight of approximately 408.4 g/mol and a high solubility in organic solvents such as THF and DMSO. This compound is known for its reactivity in organophosphorus chemistry and its ability to act as a ligand in transition metal catalysis.
How is (2S)-1-(Diphenylphosphino)-3-phenyl-2-propanamine (CAS: 146476-38-2) typically synthesized?
The compound (2S)-1-(Diphenylphosphino)-3-phenyl-2-propanamine (CAS: 146476-38-2) is typically synthesized via a multi-step process involving the coupling of diphenylphosphine and 3-phenyl-2-propanamine. The reaction is catalyzed by a strong base, and the product is obtained with good yield and high selectivity. The exact conditions can vary, but a common method involves using potassium hexafluorophosphate in the presence of a polar aprotic solvent.
What industries use (2S)-1-(Diphenylphosphino)-3-phenyl-2-propanamine (CAS: 146476-38-2)?
The compound (2S)-1-(Diphenylphosphino)-3-phenyl-2-propanamine (CAS: 146476-38-2) is primarily used in the pharmaceutical and chemical industries. It serves as a key ligand in transition metal catalysis, particularly in the development of chiral catalysts for the synthesis of pharmaceuticals and agrochemicals. The compound is also utilized in the production of polymers and as a ligand in organophosphorus chemistry.
What precautions should be taken when handling (2S)-1-(Diphenylphosphino)-3-phenyl-2-propanamine (CAS: 146476-38-2)?
When handling (2S)-1-(Diphenylphosphino)-3-phenyl-2-propanamine (CAS: 146476-38-2), it is important to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from heat sources and in a fume hood during use. In case of spillage, it is recommended to use absorbent material and dispose of it according to local regulations. Always consult the safety data sheet (SDS) for detailed handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
You might also like
Compound Q&A
What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?
6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...
21889-89-46-Methyl-7-oxabicycl...
Compound Q&A
What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?
4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...
906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A
What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?
2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...
49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A
What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?
2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...
24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A
What is 2-Oxopropanamide (CAS: 631-66-3)?
2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...
631-66-32-Oxopropanamide
Compound Q&A
What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?
2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...
1289040-88-52-Methyl-2-propanyl ...
Compound Q&A
What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?
NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...
2241019-57-6NAMPT inhibitor-link...
Compound Q&A
What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?
It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...
1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A
What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?
1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...
794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A
What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?
Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...
1314981-48-0Vinyl(chloromethyl)d...
![(-�+�S)--�+�-[(Diphenylphosphino)methyl]benzeneethanamine — Chemenu Inc.](https://static.chemtradehub.com/suppliers/68956cea7fc9b0c534d600e9/68956cea7fc9b0c534d600e9-logo.webp){kind=logo}
![(+�S)-+�-[(Diphenylphosphino)methyl]benzeneethanamine — BOC Sciences](https://static.chemtradehub.com/suppliers/67cec90e2b2de6e8e95a51b8/67cec90e2b2de6e8e95a51b8-logo.webp){kind=logo}