Compound Q&A
How is (2S)-1-(Diphenylphosphino)-3-phenyl-2-propanamine (CAS: 146476-38-2) typically synthesized?
Answer
The compound (2S)-1-(Diphenylphosphino)-3-phenyl-2-propanamine (CAS: 146476-38-2) is typically synthesized via a multi-step process involving the coupling of diphenylphosphine and 3-phenyl-2-propanamine. The reaction is catalyzed by a strong base, and the product is obtained with good yield and high selectivity. The exact conditions can vary, but a common method involves using potassium hexafluorophosphate in the presence of a polar aprotic solvent.
About
CAS No
146476-38-2
English Name
(2S)-1-(Diphenylphosphino)-3-phenyl-2-propanamine
Molecular Formula
C21H22NP
Molecular Weight
319.39 g/mol
SMILES
c1ccc(cc1)C[C@@H](CP(c2ccccc2)c3ccccc3)N
InChIKey
SIOSCJGIYDRXMO-IBGZPJMESA-N
Last Updated: 2026-03-22 19:38
