(3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methoxy-4-oxobutanoic acid | CAS No. 145038-52-4
(3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methoxy-4-oxobutanoic acid
Basic Information
CAS Number
145038-52-4
Molecular Formula
C20H19NO6
Molecular Weight
369.37 g/mol
AD
Basic Physical Properties
Boiling Point
609.7℃ at 760 mmHg
Flash Point
324.962 °C
Refractive Index
1.596
Synonyms & References
English
- N-9-Fluorenylmethoxycarbonylaspartic acid a-methyl ester
- (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-methoxy-4-oxobutanoic acid
- Fmoc-L-aspartic acid alpha-methyl ester
- HY-W041982
- CS-W022722
- DTXSID70654094
- A847859
- (3S)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methoxy-4-oxobutanoic acid
- (S)-3-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-methoxy-4-oxobutanoic acid;Fmoc-L-aspartic acid alpha methyl ester;N-Fmoc-L-aspartic Acid Methyl Ester
- (3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methoxy-4-oxobutanoic acid
- L-Aspartic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 1-methyl ester
- AKOS016002173
- MFCD03701473
- 145038-52-4
- M03407
- (3S)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-4-methoxy-4-oxobutanoic acid (non-preferred name)
- EN300-1556616
- N-Fmoc-L-aspartic Acid Methyl Ester
- F11940
- Q-101540
- 1-Methyl hydrogen N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-aspartate
- DS-13843
- Fmoc-Asp-OMe
- (S)-3-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-methoxy-4-oxobutanoic acid
- J-300076
- N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-aspartic acid alpha-methyl ester
- FMOC-L-ASP-OME
- S-145038-52-4
- (3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methoxy-4-oxobutanoic acid, AldrichCPR
- FMOC-ASP-OME
- Fmoc-L-aspartic acid α-methyl ester
MDL Number
MFCD03701473
Customs Code
2924299090
FAQ
What are the physical and chemical properties of (3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methoxy-4-oxobutanoic acid (CAS: 145038-52-4)?
This compound is a colorless crystalline solid with a molecular weight of approximately 458.46 g/mol. It exhibits moderate solubility in common organic solvents like methanol and ethanol. Chemically, it is reactive towards nucleophiles and undergoes hydrolysis under basic conditions. It is stable under normal storage conditions but should be stored away from moisture and strong acids.
How is (3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methoxy-4-oxobutanoic acid (CAS: 145038-52-4) typically synthesized?
This compound is typically synthesized through multi-step reactions, starting with the coupling of fluoren-9-ylmethanol and an amino acid derivative. Key steps include protecting group chemistry, coupling reactions, and deprotection. The overall yield is moderate, around 50-60%, and the process requires careful control of pH and temperature to achieve high selectivity.
What industries use (3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methoxy-4-oxobutanoic acid (CAS: 145038-52-4)?
This compound is used in the pharmaceutical industry for the synthesis of certain bioactive compounds. It also finds applications in the polymer industry, where it serves as a monomer for producing functional polymers. Additionally, it is used in sensor technology for its reactivity and in semiconductor manufacturing due to its chemical properties.
What precautions should be taken when handling (3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methoxy-4-oxobutanoic acid (CAS: 145038-52-4)?
When handling this compound, it is essential to use gloves, goggles, and a lab coat to protect against skin contact and inhalation. Ensure that all manipulations are conducted in a fume hood to minimize exposure. Spills should be cleaned up with caution using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed information on proper handling and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
You might also like
Compound Q&A
What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?
6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...
21889-89-46-Methyl-7-oxabicycl...
Compound Q&A
What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?
4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...
906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A
What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?
2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...
49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A
What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?
2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...
24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A
What is 2-Oxopropanamide (CAS: 631-66-3)?
2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...
631-66-32-Oxopropanamide
Compound Q&A
What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?
2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...
1289040-88-52-Methyl-2-propanyl ...
Compound Q&A
What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?
NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...
2241019-57-6NAMPT inhibitor-link...
Compound Q&A
What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?
It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...
1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A
What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?
1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...
794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A
What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?
Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...
1314981-48-0Vinyl(chloromethyl)d...
![(3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methoxy-4-oxobutanoic acid — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}
![(3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methoxy-4-oxobutanoic acid — HePeng （ ShangHai ） Biotechnology Co Ltd](https://static.chemtradehub.com/suppliers/67ceccf22b2de6e8e95a5e0f/67ceccf22b2de6e8e95a5e0f-logo.webp){kind=logo}
![(3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methoxy-4-oxobutanoic acid — JiErShengHua （ ShangHai ） Co Ltd](https://static.chemtradehub.com/suppliers/67cecb182b2de6e8e95a5951/67cecb182b2de6e8e95a5951-logo.webp){kind=logo}
![(3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methoxy-4-oxobutanoic acid — Nanjing Peptide Industry Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67cdfc1057537e5c8069b0ad/67cdfc1057537e5c8069b0ad-logo.webp){kind=logo}