(2S)-(2-Chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride (1:1) | CAS No. 144750-42-5

(2S)-(2-Chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride (1:1)

Basic Information

CAS Number

144750-42-5

Molecular Formula

C15H15Cl2NO2S

Molecular Weight

344.26 g/mol

AD

Basic Physical Properties

Melting Point

147-155°C (dec.)

Solubility

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

c1ccc(c(c1)[C@@H](C(=O)O)N2CCc3c(ccs3)C2)Cl.Cl

InChI

InChI=1S/C15H14ClNO2S.ClH/c16-12-4-2-1-3-11(12)14(15(18)19)17-7-5-13-10(9-17)6-8-20-13;/h1-4,6,8,14H,5,7,9H2,(H,18,19);1H/t14-;/m0./s1

InChIKey

FOKSIOUPGDBSLC-UQKRIMTDSA-N

LogP

4.007300000000003

Topological Polar Surface Area

40.54 Ų

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

368

Synonyms & References

English

  • (S)-2-(2-Chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride
  • Clopidogrel Carboxylic Acid Hydrochloride
  • (S)-2-(2-Chlorophenyl)-2-(6,7-dihydrothieno-[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride
  • CLOPIDOGREL BISULFATE IMPURITY A
  • Clopidogrel Related Compound A
  • (S)-(2-Chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic acid hydrochloride
  • (S)-(o-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic acid, hydrochloride
  • Clopidogrel Related CoMpound A,(S)-(o-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic acid, hydrochloride
  • Clopidogrel impurity A
  • FOKSIOUPGDBSLC-UQKRIMTDSA-N
  • AK109525
  • Clopidogrel carboxylic acid HCl
  • BC644942
  • BC228260
  • ST2402765
  • AX8221119
  • AB1004591
  • C
  • Clopidogrel EP Impurity A HCl

MDL Number

MFCD08063656

Customs Code

2934999090

FAQ

What are the physical and chemical properties of (2S)-(2-Chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride (CAS: 144750-42-5)?

This compound has a crystalline form and a molecular weight of approximately 395.73 g/mol. It is sparingly soluble in water and ethanol. Chemically, it is reactive towards bases and can undergo esterification and hydrolysis reactions. It is stable under normal conditions but should be stored in a cool, dry place away from strong acids and bases.

How is (2S)-(2-Chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride (CAS: 144750-42-5) typically synthesized?

The compound is typically synthesized via a multi-step process involving the reaction of a 2-chlorophenyl derivative with 6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid. Commonly, palladium catalysts are used for the coupling reaction, with high selectivity and good yields. The final step involves the addition of hydrochloric acid to form the hydrochloride salt.

What industries use (2S)-(2-Chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride (CAS: 144750-42-5)?

This compound is used in the pharmaceutical industry for its potential as a drug candidate. It is also utilized in the polymer industry as a modifier and in the development of sensors due to its unique chemical properties. Additionally, it can be explored for use in semiconductors and electronic applications.

What precautions should be taken when handling (2S)-(2-Chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride (CAS: 144750-42-5)?

When handling this compound, appropriate personal protective equipment (PPE) such as gloves and safety glasses should be worn. It should be stored in a fume hood and away from strong acids and bases. In case of a spill, it should be handled carefully and possibly neutralized with a suitable base before disposal. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety guidelines.

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