Compound Q&A
How is (2S)-(2-Chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride (CAS: 144750-42-5) typically synthesized?
Answer
![(2S)-(2-Chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride (1:1)](https://static.chemtradehub.com/structs/144/144750-42-5-dde5.webp "(2S)-(2-Chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride (1:1)")
The compound is typically synthesized via a multi-step process involving the reaction of a 2-chlorophenyl derivative with 6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid. Commonly, palladium catalysts are used for the coupling reaction, with high selectivity and good yields. The final step involves the addition of hydrochloric acid to form the hydrochloride salt.
About
CAS No
144750-42-5
English Name
(2S)-(2-Chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride (1:1)
Molecular Formula
C15H15Cl2NO2S
Molecular Weight
344.26 g/mol
SMILES
c1ccc(c(c1)[C@@H](C(=O)O)N2CCc3c(ccs3)C2)Cl.Cl
InChIKey
FOKSIOUPGDBSLC-UQKRIMTDSA-N
Last Updated: 2025-10-13 17:50
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