4-(2-Hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid | CAS No. 144690-04-0
4-(2-Hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid
Basic Information
CAS Number
144690-04-0
Molecular Formula
C10H16N2O3
Molecular Weight
212.25 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- 4-(1-hydroxy-1-methylethyl)-2-propylimidazole-5-carboxylic acid
- 4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid
- 5-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-4-carboxylic acid
- 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylic acid
MDL Number
MFCD24483971
FAQ
What are the physical and chemical properties of 4-(2-Hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid (CAS: 144690-04-0)?
4-(2-Hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid is a white to off-white crystalline solid with a molecular weight of approximately 300.4 g/mol. It is slightly soluble in water and ethanol. The compound exhibits acidic properties due to the carboxylic acid group, making it reactive towards bases and nucleophiles.
How is 4-(2-Hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid (CAS: 144690-04-0) typically synthesized?
4-(2-Hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid can be synthesized via a multi-step process involving condensation of 2-propylimidazole-5-carboxylic acid with 2-hydroxypropan-2-yl bromide. The reaction is typically performed under reflux conditions in an inert solvent like toluene, with the use of a catalyst such as sodium hydride to improve the yield.
What industries use 4-(2-Hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid (CAS: 144690-04-0)?
4-(2-Hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid finds applications in the pharmaceutical industry as a potential drug candidate due to its structural characteristics. It is also utilized in the development of sensors and as a functional group in polymer chemistry for its reactivity and solubility properties.
What precautions should be taken when handling 4-(2-Hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid (CAS: 144690-04-0)?
When handling 4-(2-Hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid, it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Handle in a fume hood to avoid inhalation and ensure proper ventilation. Store the compound in a dry, cool place away from direct sunlight. In case of skin contact, wash with soap and water. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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