(1R,2S)-2-Fluorocyclopropanaminium 4-methylbenzenesulfonate | CAS No. 143062-84-4

(1R,2S)-2-Fluorocyclopropanaminium 4-methylbenzenesulfonate

Basic Information

CAS Number

143062-84-4

Molecular Formula

C10H14FNO3S

Molecular Weight

247.29 g/mol

AD

Basic Physical Properties

Boiling Point

418.2°C at 760 mmHg

CC1=CC=C(C=C1)S(=O)(=O)O.C1C(C1F)N

InChI

InChI=1S/C7H8O3S.C3H6FN/c1-6-2-4-7(5-3-6)11(8,9)10;4-2-1-3(2)5/h2-5H,1H3,(H,8,9,10);2-3H,1,5H2/t;2-,3+/m.0/s1

InChIKey

XUWZMHVPMZXIRU-LMLSDSMGSA-N

LogP

1.2972200000000003

Topological Polar Surface Area

80.39 Ų

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

253

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H332 Harmful if inhaled
Acute toxicity, inhalation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • XUWZMHVPMZXIRU-LMLSDSMGSA-N
  • (1R,2S)-FLUOROCYCLOPROPYLAMINE TOSYLATE
  • AKOS015854141
  • 143062-84-4
  • EN300-7396647
  • AC-23953
  • (1R,2S)-2-Fluorocyclopropan-1-amine 4-methylbenzenesulfonate
  • (1r,2s)-2-fluorocyclopropylamine p-toluenesulfonic acid salt
  • Z2306780869
  • (1R,2S)-2-fluorocyclopropan-1-amine; 4-methylbenzene-1-sulfonic acid
  • (1R,2S)-2-fluorocyclopropan-1-amine 4-methylbenzene-1-sulfonic acid
  • CS3396
  • DS-3733
  • (1R,2S)-2-Fluorocyclopropanamine 4-methylbenzenesulfonate
  • 143062-73-1
  • SCHEMBL1477176
  • AKOS016004123
  • cis-2-Fluorocyclopropanamine-4-methylbenzenesulfonate
  • (cis)-2-fluorocyclopropanamine4-methylbenzenesulfonate
  • EN300-1721647
  • (1R, 2S)-2-fluoro-1-cyclopropylamine p-toluene sulfonate
  • CS-W005880
  • (1R, 2S)-2-Fluorocyclopropylamine 4-methylbenzenesulfonate
  • 2-(s)-fluoro-1-(r)-cyclopropylamine p-toluenesulfonic acid salt
  • rac-(1R,2S)-2-fluorocyclopropan-1-amine; 4-methylbenzene-1-sulfonic acid
  • (1R,2S)-2-fluorocyclopropan-1-amine;4-methylbenzenesulfonic acid
  • MFCD01861147
  • AC-22722
  • Cyclopropanamine, 2-fluoro-, cis-, 4-methylbenzenesulfonate
  • 4-Methylbenzene-1-sulfonic acid--(1R,2S)-2-fluorocyclopropan-1-amine (1/1)
  • DTXSID00693592

MDL Number

MFCD01861147

Customs Code

2942000000

FAQ

What are the physical and chemical properties of (1R,2S)-2-Fluorocyclopropanaminium 4-methylbenzenesulfonate (CAS: 143062-84-4)?

(1R,2S)-2-Fluorocyclopropanaminium 4-methylbenzenesulfonate has a crystalline form with a molecular weight of approximately 269.2 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. The compound is known for its stability under neutral conditions but can be reactive in acidic or strongly basic environments. It is typically used in organic synthesis and pharmaceutical applications due to its unique chemical structure.

How is (1R,2S)-2-Fluorocyclopropanaminium 4-methylbenzenesulfonate (CAS: 143062-84-4) typically synthesized?

(1R,2S)-2-Fluorocyclopropanaminium 4-methylbenzenesulfonate is usually synthesized via a multistep process involving fluorocyclopropanamine and 4-methylbenzenesulfonyl chloride. The reaction is typically carried out in the presence of a base, such as triethylamine, under anhydrous conditions. The yield and selectivity can be optimized using specific catalysts and reaction conditions, making it a valuable intermediate in organic synthesis.

What industries use (1R,2S)-2-Fluorocyclopropanaminium 4-methylbenzenesulfonate (CAS: 143062-84-4)?

(1R,2S)-2-Fluorocyclopropanaminium 4-methylbenzenesulfonate is primarily used in pharmaceuticals and organic synthesis due to its unique chemical structure. It can also find applications in the production of polymers and as a reagent in sensor and semiconductor manufacturing. Its use in these industries is driven by its reactivity and stability in various chemical environments.

What precautions should be taken when handling (1R,2S)-2-Fluorocyclopropanaminium 4-methylbenzenesulfonate (CAS: 143062-84-4)?

When handling (1R,2S)-2-Fluorocyclopropanaminium 4-methylbenzenesulfonate, it is important to wear appropriate personal protective equipment (PPE) including gloves, lab coat, and safety goggles. The compound should be stored away from heat sources and in a well-ventilated area. In case of a spill, it should be handled with care, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal procedures.

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