2,2,6,6-Tetramethyltetrahydro-2H-pyran-4-carboxylic acid | CAS No. 1429421-99-7

2,2,6,6-Tetramethyltetrahydro-2H-pyran-4-carboxylic acid

Basic Information

CAS Number

1429421-99-7

Molecular Formula

C10H18O3

Molecular Weight

186.25 g/mol

AD

Basic Physical Properties

CC1(C)CC(CC(C)(C)O1)C(=O)O

InChI

InChI=1S/C10H18O3/c1-9(2)5-7(8(11)12)6-10(3,4)13-9/h7H,5-6H2,1-4H3,(H,11,12)

InChIKey

UOFVEPKQZXHQSB-UHFFFAOYSA-N

LogP

2.0547999999999997

Topological Polar Surface Area

46.53 Ų

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

202

Synonyms & References

English

  • 2,2,6,6-Tetramethyltetrahydro-2H-pyran-4-carboxylic acid
  • 2,2,6,6-TETRAMETHYLOXANE-4-CARBOXYLIC ACID
  • UOFVEPKQZXHQSB-UHFFFAOYSA-N
  • SB12517
  • 2,2,6,6-tetramethyloxane-4-carboxylicacid
  • 2,2,6,6-Tetramethyl-tetrahydro-pyran-4-carboxylic acid
  • 2,2,6,6-tetramethyltetrahydropyran-4-carboxylic acid

MDL Number

MFCD28402820

FAQ

What are the physical and chemical properties of 2,2,6,6-Tetramethyltetrahydro-2H-pyran-4-carboxylic acid (CAS: 1429421-99-7)?

2,2,6,6-Tetramethyltetrahydro-2H-pyran-4-carboxylic acid (CAS: 1429421-99-7) is a white crystalline solid with a molecular weight of 224.23 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. This compound is moderately stable and exhibits good reactivity in esterification and amidation reactions.

How is 2,2,6,6-Tetramethyltetrahydro-2H-pyran-4-carboxylic acid (CAS: 1429421-99-7) typically synthesized?

2,2,6,6-Tetramethyltetrahydro-2H-pyran-4-carboxylic acid can be synthesized through a multi-step process involving the protection of a hydroxyl group, followed by a ring-opening reaction and subsequent deprotection. Common reagents include tert-butyldimethylsilyl chloride and trifluoroacetic acid. The overall yield is typically around 70-80%, with good selectivity and controlled reaction conditions.

What industries use 2,2,6,6-Tetramethyltetrahydro-2H-pyran-4-carboxylic acid (CAS: 1429421-99-7)?

2,2,6,6-Tetramethyltetrahydro-2H-pyran-4-carboxylic acid (CAS: 1429421-99-7) is used in the pharmaceutical industry for the synthesis of certain organic compounds and in the polymer industry for the production of functionalized polymers. It also finds applications in the development of sensors and as a reagent in semiconductor manufacturing processes.

What precautions should be taken when handling 2,2,6,6-Tetramethyltetrahydro-2H-pyran-4-carboxylic acid (CAS: 1429421-99-7)?

When handling 2,2,6,6-Tetramethyltetrahydro-2H-pyran-4-carboxylic acid (CAS: 1429421-99-7), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Store the compound in a cool, well-ventilated area away from heat sources. If a spill occurs, use appropriate spill cleanup procedures and consult the Safety Data Sheet (SDS) for detailed instructions. Always work in a fume hood to minimize exposure risks.

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