N-[(1R)-1-(5-Chloro-2-hydroxyphenyl)ethyl]-4-methylbenzenesulfonamide | CAS No. 1421840-44-9
N-[(1R)-1-(5-Chloro-2-hydroxyphenyl)ethyl]-4-methylbenzenesulfonamide
Basic Information
CAS Number
1421840-44-9
Molecular Formula
C15H16ClNO3S
Molecular Weight
325.81 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- (R)-N-(1-(5-chloro-2-hydroxyphenyl)ethyl)-4-methylbenzenesulfonamide
- N-[(1R)-1-(5-chloro-2-hydroxy-phenyl)ethyl]-4-methyl-benzenesulfonamide
MDL Number
MFCD28133446
FAQ
What are the physical and chemical properties of N-[(1R)-1-(5-Chloro-2-hydroxyphenyl)ethyl]-4-methylbenzenesulfonamide (CAS: 1421840-44-9)?
N-[(1R)-1-(5-Chloro-2-hydroxyphenyl)ethyl]-4-methylbenzenesulfonamide (CAS: 1421840-44-9) is a crystalline solid with a molecular weight of approximately 348.23 g/mol. It has limited solubility in water and good solubility in organic solvents. The compound is moderately reactive, particularly towards nucleophiles and bases. It shows good stability under normal storage conditions.
How is N-[(1R)-1-(5-Chloro-2-hydroxyphenyl)ethyl]-4-methylbenzenesulfonamide (CAS: 1421840-44-9) typically synthesized?
N-[(1R)-1-(5-Chloro-2-hydroxyphenyl)ethyl]-4-methylbenzenesulfonamide (CAS: 1421840-44-9) is typically synthesized via a multistep process involving the coupling of 4-methylbenzenesulfonyl chloride with 1-(5-chloro-2-hydroxyphenyl)ethylamine, often catalyzed by a phase-transfer catalyst. The yield is around 80%, and the process involves careful control of pH and temperature to ensure selectivity and high purity.
What industries use N-[(1R)-1-(5-Chloro-2-hydroxyphenyl)ethyl]-4-methylbenzenesulfonamide (CAS: 1421840-44-9)?
N-[(1R)-1-(5-Chloro-2-hydroxyphenyl)ethyl]-4-methylbenzenesulfonamide (CAS: 1421840-44-9) is used in the pharmaceutical industry for its potential as a therapeutic agent. It may also be used in the development of sensors and in other chemical applications where its specific chemical properties are advantageous.
What precautions should be taken when handling N-[(1R)-1-(5-Chloro-2-hydroxyphenyl)ethyl]-4-methylbenzenesulfonamide (CAS: 1421840-44-9)?
When handling N-[(1R)-1-(5-Chloro-2-hydroxyphenyl)ethyl]-4-methylbenzenesulfonamide (CAS: 1421840-44-9), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a cool, dry place away from sources of heat and light. Use a fume hood during handling to minimize inhalation risk. In case of spill, follow standard safety protocols and consult the safety data sheet (SDS) for specific instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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