N-[(1R)-1-(5-Chloro-2-hydroxyphenyl)ethyl]-4-methylbenzenesulfonamide(CAS: 1421840-44-9)

N-[(1R)-1-(5-Chloro-2-hydroxyphenyl)ethyl]-4-methylbenzenesulfonamide (CAS: 1421840-44-9) is a crystalline solid with a molecular weight of approximately 348.23 g/mol. It has limited solubility in water and good solubility in organic solvents. The compound is moderately reactive, particularly towards nucleophiles and bases. It shows good stability under normal storage conditions.

N-[(1R)-1-(5-Chloro-2-hydroxyphenyl)ethyl]-4-methylbenzenesulfonamide (CAS: 1421840-44-9) is typically synthesized via a multistep process involving the coupling of 4-methylbenzenesulfonyl chloride with 1-(5-chloro-2-hydroxyphenyl)ethylamine, often catalyzed by a phase-transfer catalyst. The yield is around 80%, and the process involves careful control of pH and temperature to ensure selectivity and high purity.

N-[(1R)-1-(5-Chloro-2-hydroxyphenyl)ethyl]-4-methylbenzenesulfonamide (CAS: 1421840-44-9) is used in the pharmaceutical industry for its potential as a therapeutic agent. It may also be used in the development of sensors and in other chemical applications where its specific chemical properties are advantageous.

When handling N-[(1R)-1-(5-Chloro-2-hydroxyphenyl)ethyl]-4-methylbenzenesulfonamide (CAS: 1421840-44-9), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a cool, dry place away from sources of heat and light. Use a fume hood during handling to minimize inhalation risk. In case of spill, follow standard safety protocols and consult the safety data sheet (SDS) for specific instructions.