N-(2-Butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)-N-(methylsulfonyl)methanesulfonamide | CAS No. 141626-57-5

N-(2-Butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)-N-(methylsulfonyl)methanesulfonamide

Basic Information

CAS Number

141626-57-5

Molecular Formula

C32H46N2O7S2

Molecular Weight

634.86 g/mol

AD

Basic Physical Properties

CCCCc1c(c2cc(ccc2o1)N(S(=O)(=O)C)S(=O)(=O)C)C(=O)c3ccc(cc3)OCCCN(CCCC)CCCC

InChI

InChI=1S/C32H46N2O7S2/c1-6-9-13-30-31(28-24-26(16-19-29(28)41-30)34(42(4,36)37)43(5,38)39)32(35)25-14-17-27(18-15-25)40-23-12-22-33(20-10-7-2)21-11-8-3/h14-19,24H,6-13,20-23H2,1-5H3

InChIKey

IKGSSECULYFYER-UHFFFAOYSA-N

LogP

6.403100000000007

Topological Polar Surface Area

114.19999999999999 Ų

Hydrogen Bond Donor/Acceptor

0 / 9

Synonyms & References

English

  • N-Mesyldronedarone
  • N-(2-butyl-3-(4-(3-(dibutylamino)propoxy)-benzoyl)benzofuran-5-yl)-N-(methylsulfonyl)methanesulfonamide
  • N-(2-Butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)benzofuran-5-yl)-N-(methylsulfonyl)methanesulfonamide
  • hydrochloride (1:1)

FAQ

What are the physical and chemical properties of N-(2-Butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)-N-(methylsulfonyl)methanesulfonamide (CAS: 141626-57-5)?

N-(2-Butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)-N-(methylsulfonyl)methanesulfonamide is a white crystalline solid with a molecular weight of approximately 786.8 g/mol. It has low solubility in water but is more soluble in organic solvents like DMF and DMSO. Reactivity is moderate with typical amide and sulfonamide functionalities. It is stable under normal conditions but should be stored in a cool, dry place away from light.

How is N-(2-Butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)-N-(methylsulfonyl)methanesulfonamide (CAS: 141626-57-5) typically synthesized?

This compound can be synthesized through multistep reactions involving the coupling of 2-butyl-1-benzofuran-5-carboxylic acid with 4-[3-(dibutylamino)propoxy]benzoyl chloride, followed by the addition of N-(methylsulfonyl)methanesulfonamide. The reaction usually requires the use of a base like triethylamine and a suitable solvent such as dichloromethane. The overall yield is moderate, around 50-60%.

What industries use N-(2-Butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)-N-(methylsulfonyl)methanesulfonamide (CAS: 141626-57-5)?

This compound is primarily used in the pharmaceutical industry for its potential biological activities, although its exact applications are not widely documented. It may also find uses in sensor technology and other specialized chemical applications due to its unique chemical structure.

What precautions should be taken when handling N-(2-Butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)-N-(methylsulfonyl)methanesulfonamide (CAS: 141626-57-5)?

When handling this compound, it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly rinsed. Refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.

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