N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine | CAS No. 1400634-44-7

N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine

Basic Information

CAS Number

1400634-44-7

Molecular Formula

C30H55N9O10

Molecular Weight

701.81 g/mol

AD

Basic Physical Properties

OCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)O)C(O)C)CCCN=C(N)N)C(C)C)C(C)C)C(C)C)NC(=O)C

InChI

InChI=1S/C30H55N9O10/c1-13(2)20(26(45)35-18(10-9-11-33-30(31)32)24(43)39-23(16(7)41)29(48)49)37-28(47)22(15(5)6)38-27(46)21(14(3)4)36-25(44)19(12-40)34-17(8)42/h13-16,18-23,40-41H,9-12H2,1-8H3,(H,34,42)(H,35,45)(H,36,44)(H,37,47)(H,38,46)(H,39,43)(H,48,49)(H4,31,32,33)

InChIKey

BETZBTCJWHBFIG-UHFFFAOYSA-N

LogP

-3.6056000000000026

Topological Polar Surface Area

316.7599999999999 Ų

Hydrogen Bond Donor/Acceptor

13 / 19

Complexity

1190

Synonyms & References

English

  • Acetyl Hexapeptide-38
  • Acetyl hexapeptide -38
  • Ac-DL-Ser-DL-Val-DL-Val-DL-Val-DL-Arg-DL-xiThr-OH

FAQ

What are the physical and chemical properties of N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine (CAS: 1400634-44-7)?

N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine is a complex peptide. It is a white to off-white crystalline solid. The molecular weight is approximately 1048.6 g/mol. It is slightly soluble in water and ethanol. The compound shows moderate reactivity, particularly towards nucleophiles and reducing agents.

How is N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine (CAS: 1400634-44-7) typically synthesized?

N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine is synthesized via solid-phase peptide synthesis. The key steps involve the stepwise addition of protected amino acids, followed by coupling, deprotection, and side-chain modifications. Commonly, Fmoc chemistry is used, and the final product is obtained with a yield of around 70-80%.

What industries use N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine (CAS: 1400634-44-7)?

N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine is primarily used in pharmaceuticals for its anti-inflammatory and immunomodulatory properties. It also finds applications in research for studying protein-protein interactions and as a model compound in peptide chemistry. Some industries include biotechnology, pharmaceuticals, and academic research.

What precautions should be taken when handling N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine (CAS: 1400634-44-7)?

When handling N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine, wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work in a well-ventilated fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.

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