N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine(CAS: 1400634-44-7)

N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine is a complex peptide. It is a white to off-white crystalline solid. The molecular weight is approximately 1048.6 g/mol. It is slightly soluble in water and ethanol. The compound shows moderate reactivity, particularly towards nucleophiles and reducing agents.

N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine is synthesized via solid-phase peptide synthesis. The key steps involve the stepwise addition of protected amino acids, followed by coupling, deprotection, and side-chain modifications. Commonly, Fmoc chemistry is used, and the final product is obtained with a yield of around 70-80%.

N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine is primarily used in pharmaceuticals for its anti-inflammatory and immunomodulatory properties. It also finds applications in research for studying protein-protein interactions and as a model compound in peptide chemistry. Some industries include biotechnology, pharmaceuticals, and academic research.

When handling N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine, wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work in a well-ventilated fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.