Compound Q&A

How is N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine (CAS: 1400634-44-7) typically synthesized?

Answer

N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine
N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine is synthesized via solid-phase peptide synthesis. The key steps involve the stepwise addition of protected amino acids, followed by coupling, deprotection, and side-chain modifications. Commonly, Fmoc chemistry is used, and the final product is obtained with a yield of around 70-80%.

About

English Name N-Acetyl-L-seryl-L-valyl-L-valyl-L-valyl-N~5~-(diaminomethylene)-L-ornithyl-L-threonine
Molecular Formula C30H55N9O10
Molecular Weight 701.81 g/mol
SMILES OCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)O)C(O)C)CCCN=C(N)N)C(C)C)C(C)C)C(C)C)NC(=O)C
InChIKey BETZBTCJWHBFIG-UHFFFAOYSA-N
Last Updated: 2025-10-13 11:18

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