3-Cyclopentylpropanoic acid

Basic Information

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CAS Number

140-77-2

Molecular Formula

C8H14O2

Molecular Weight

142.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Physical Properties

Boiling Point

123°C/6mmHg

Refractive Index

n20/D 1.457(lit.)

SMILES

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C1CCC(C1)CCC(=O)O

InChI

InChI=1S/C8H14O2/c9-8(10)6-5-7-3-1-2-4-7/h7H,1-6H2,(H,9,10)

InChIKey

ZRPLANDPDWYOMZ-UHFFFAOYSA-N

LogP

2.0414000000000003

Topological Polar Surface Area

37.3 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

114

Safety Information

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Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 3 Class 3

Synonyms & References

English

Propionic acid, 3-cyclopentyl-
Cyclopentylpropionic acid
A3041
140-77-2
Q5200280
3-Cyclopentyl-propionic acid
cypionic acid
AI3-14247
CS-W018280
AM84371
CHEMBL1230184
NCGC00166228-01
Cyclopentanepropionic acid
SCHEMBL2800
EINECS 205-433-0
3-Cylcopentylpropanoic acid
MFCD00001392
CYCLOPENTYLPROPANOIC ACID [USP-RS]
3-Cylcopentylpropanoicacid
J-512367
F2191-0135
NSC 8771
DTXSID4059700
3-Cyclopentylpropionic acid, 98%
3-Cyclopentylpropanoic acid
Cyclopentanepropanoic acid
FT-0631815
NS00024564
3-cyclopentyl propionic acid
3-Cyclopentylpropionicacid
Z104478044

MDL Number

MFCD00001392

Customs Code

2916209090

FAQ

What are the physical and chemical properties of 3-Cyclopentylpropanoic acid (CAS: 140-77-2)?

3-Cyclopentylpropanoic acid is a colorless crystalline solid with a molecular weight of approximately 154.26 g/mol. It has a pKa of around 4.9 and is slightly soluble in water. The compound is reactive towards esterification and can undergo acid-catalyzed reactions. It has a melting point of 67-68°C and a boiling point of about 255°C. It is soluble in organic solvents like ethanol and acetone.

How is 3-Cyclopentylpropanoic acid (CAS: 140-77-2) typically synthesized?

3-Cyclopentylpropanoic acid is typically synthesized by the esterification of cyclopentyl propyl alcohol with acetic acid using an acid catalyst such as concentrated sulfuric acid. The reaction is usually conducted at room temperature, and the product can be isolated by recrystallization. The yield is generally around 80-90%. The selectivity and yield can be improved by optimizing reaction conditions and using more sophisticated catalysts.

What industries use 3-Cyclopentylpropanoic acid (CAS: 140-77-2)?

3-Cyclopentylpropanoic acid finds applications in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also used in the polymer industry for the production of certain types of plastics and coatings. Additionally, it is utilized in the sensor industry for the development of chemical sensors and in semiconductor manufacturing for specific applications.

What precautions should be taken when handling 3-Cyclopentylpropanoic acid (CAS: 140-77-2)?

When handling 3-Cyclopentylpropanoic acid, it is important to use appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. Work should be done in a well-ventilated area or fume hood to avoid inhalation. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage. Proper storage should be in a cool, dry place away from incompatible materials.