(2-Formyl-4-methoxyphenyl)boronic acid

Basic Information

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CAS Number

139962-95-1

Molecular Formula

C8H9BO4

Molecular Weight

179.97 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

161°C

Boiling Point

395.2°C at 760 mmHg

SMILES

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B(C1=C(C=C(C=C1)OC)C=O)(O)O

InChI

InChI=1S/C8H9BO4/c1-13-7-2-3-8(9(11)12)6(4-7)5-10/h2-5,11-12H,1H3

InChIKey

ZSSNGMFKYFBOAG-UHFFFAOYSA-N

LogP

-0.8125000000000002

Topological Polar Surface Area

66.76 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

174

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Class KEEP COLD Class KEEP COLD

Synonyms & References

English

2-BORONO-5-METHOXYBENZALDEHYDE
AM86585
2-formyl-4-methoxyphenylboronicacid
DTXSID00370255
SY033602
I12185
A807604
Boronic acid, B-(2-formyl-4-methoxyphenyl)-
AB08871
139962-95-1
(2-formyl-4-methoxyphenyl)boronic acid
2-Formyl-4-methoxyphenylboronic acid
2-FORMYL-4-METHOXYBENZENEBORONIC ACID
J-509536
AKOS004116320
4-Methoxy-2-formylphenylboronic acid
CS-0100651
FT-0612457
2-Formyl-4-methoxyphenylboronic acid, 97%
EN300-7383696
MFCD01319043
F1108
ZSSNGMFKYFBOAG-UHFFFAOYSA-N
SCHEMBL50949
PS-9480
2-Formyl-4-methoxyphenylboronic Acid (contains varying amounts of Anhydride)
2-Formyl-4-methoxybenzeneboronic acid
2-Formyl-4-methoxybenzeneboronic Acid (contains varying amounts of Anhydride)
PubChem7993
(2-formyl-4-methoxy-phenyl)boronic Acid
OR7336

MDL Number

MFCD01319043

FAQ

What are the physical and chemical properties of (2-Formyl-4-methoxyphenyl)boronic acid (CAS: 139962-95-1)?

(2-Formyl-4-methoxyphenyl)boronic acid is a crystalline solid with a molecular weight of approximately 245.21 g/mol. It has a low water solubility but is soluble in organic solvents. This compound is known for its reactivity, particularly in Suzuki coupling reactions, making it valuable in organic synthesis.

How is (2-Formyl-4-methoxyphenyl)boronic acid (CAS: 139962-95-1) typically synthesized?

(2-Formyl-4-methoxyphenyl)boronic acid is commonly synthesized through the coupling of 2-formyl-4-methoxyphenol with boronic acid using a suitable catalyst, such as palladium(II) acetate and triphenylphosphine under microwave conditions. The reaction yield is typically around 70-80%, with good selectivity.

What industries use (2-Formyl-4-methoxyphenyl)boronic acid (CAS: 139962-95-1)?

(2-Formyl-4-methoxyphenyl)boronic acid is primarily used in the pharmaceutical and chemical industries for the synthesis of various drugs and organic compounds. It is also utilized in the development of sensors and as a reagent in semiconductor manufacturing.

What precautions should be taken when handling (2-Formyl-4-methoxyphenyl)boronic acid (CAS: 139962-95-1)?

When handling (2-Formyl-4-methoxyphenyl)boronic acid, it is important to use personal protective equipment (PPE), including gloves and safety glasses. Store the compound in a fume hood and handle it in a well-ventilated area. In case of a spill, use appropriate absorbents and follow the Material Safety Data Sheet (MSDS) guidelines for disposal.