(2-Formyl-4-methoxyphenyl)boronic acid(CAS: 139962-95-1)

(2-Formyl-4-methoxyphenyl)boronic acid is a crystalline solid with a molecular weight of approximately 245.21 g/mol. It has a low water solubility but is soluble in organic solvents. This compound is known for its reactivity, particularly in Suzuki coupling reactions, making it valuable in organic synthesis.

(2-Formyl-4-methoxyphenyl)boronic acid is commonly synthesized through the coupling of 2-formyl-4-methoxyphenol with boronic acid using a suitable catalyst, such as palladium(II) acetate and triphenylphosphine under microwave conditions. The reaction yield is typically around 70-80%, with good selectivity.

(2-Formyl-4-methoxyphenyl)boronic acid is primarily used in the pharmaceutical and chemical industries for the synthesis of various drugs and organic compounds. It is also utilized in the development of sensors and as a reagent in semiconductor manufacturing.

When handling (2-Formyl-4-methoxyphenyl)boronic acid, it is important to use personal protective equipment (PPE), including gloves and safety glasses. Store the compound in a fume hood and handle it in a well-ventilated area. In case of a spill, use appropriate absorbents and follow the Material Safety Data Sheet (MSDS) guidelines for disposal.