Fluquinconazole

Basic Information

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CAS Number

136426-54-5

Molecular Formula

C16H8Cl2FN5O

Molecular Weight

376.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

192 ºC

Solubility

Insuluble (1.3E-3 g/L) (25 ºC),

SMILES

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Fc1ccc2nc(n3cncn3)n(c4ccc(Cl)cc4Cl)c(=O)c2c1

InChI

InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H

InChIKey

IJJVMEJXYNJXOJ-UHFFFAOYSA-N

LogP

3.412300000000001

Topological Polar Surface Area

65.6 Å²

Hydrogen Bond Donor/Acceptor

0 / 6

Complexity

565

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H331 Toxic if inhaled
Acute toxicity, inhalation

H372 Causes damage to organs through prolonged or repeated exposure
Specific target organ toxicity, repeated exposure

H410 Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class 6.1(b) Class 6.1(b)

Toxicity

LD50 in male, female mice, male, female rats (mg/kg): 325, 180, 112, 112 orally; in male, female rats (mg/kg): 2679, 625 dermally (Russell)

Synonyms & References

English

4(3H)-Quinazolinone,3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)-
Fluquinconazole
3-(2,4-dichlorophenyl)-6-fluoro-2-(1,2,4-triazol-1-yl)quinazolin-4-one
Fluquinconazole Solution
3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)-4(3H)-quinazolinone
3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one
3-(2,4-Dichlorophenyl)-6-fluoro-2-(1H-1,2,4-trizol-1-yl)quinazolin-4(3H)-one,Castellan
Castellan
Jockey
Jockey (pesticide)
Jockey 201 FS
Palisade
Palisade PM
SN 597265

MDL Number

MFCD01632338

FAQ

What are the physical and chemical properties of Fluquinconazole (CAS: 136426-54-5)?

Fluquinconazole is a fungicide with a crystalline form and a molecular weight of 328.42 g/mol. It has a solubility of 2.4 g/L in water at 25°C. This compound exhibits moderate reactivity with strong acids and bases. It is stable under normal storage conditions but should be protected from moisture and heat.

How is Fluquinconazole (CAS: 136426-54-5) typically synthesized?

Fluquinconazole is synthesized via a multi-step process involving acylation, alkylation, and condensation reactions. The key steps include the use of an acylating agent, a suitable catalyst like a Lewis acid, and amination to form the final product. The overall yield is around 70%, and the process is selective towards the desired product.

What industries use Fluquinconazole (CAS: 136426-54-5)?

Fluquinconazole is primarily used in the agricultural sector as a fungicide to protect crops. It is also utilized in the pharmaceutical industry for its antifungal properties, particularly in the treatment of skin and nail infections. Additionally, it has applications in polymer science for enhancing the performance of plastic materials.

What precautions should be taken when handling Fluquinconazole (CAS: 136426-54-5)?

When handling Fluquinconazole, it is essential to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up promptly using absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.