2-Methyl-7-nitro-2H-indazole

Basic Information

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CAS Number

13436-58-3

Molecular Formula

C8H7N3O2

Molecular Weight

177.16 g/mol

Basic Physical Properties

Boiling Point

364.5°Cat760mmHg

Density

1.42

Flash Point

174.2°C

Refractive Index

1.676

SMILES

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CN1C=C2C=CC=C(C2=N1)[N+](=O)[O-]

InChI

InChI=1S/C8H7N3O2/c1-10-5-6-3-2-4-7(11(12)13)8(6)9-10/h2-5H,1H3

InChIKey

IFVSROJIKNMTNX-UHFFFAOYSA-N

LogP

2.00470

Complexity

216

Synonyms & References

English

SCHEMBL19028888
BRN 0164024
HMS2622I16
SMR000337102
CCRIS 3254
CHEMBL608715
CS-0137946
9P-912
A806773
7-Nitro-2-methylindazole
IFVSROJIKNMTNX-UHFFFAOYSA-
InChI=1/C8H7N3O2/c1-10-5-6-3-2-4-7(11(12)13)8(6)9-10/h2-5H,1H3
2-methyl-7-nitro-indazole
2H-Indazole, 2-methyl-7-nitro-
W-205435
2-methyl-7-nitro-2H-indazole
F14519
2-methyl-7-nitroindazole
2-N-Methyl-7-nitroindazole
FT-0645789
MLS000721476
MFCD01719664
13436-58-3
AKOS015993793
NCGC00246564-01
DTXSID00158671
2-Methyl-7-nitro-2H-indazole
2-Methyl-7-nitro-1H-indazole
7-NITRO-2-METHYLINDAZOLE
2H-Indazole,2-methyl-7-nitro
2-Methyl-7-nitroindazol

MDL Number

MFCD01719664

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-Methyl-7-nitro-2H-indazole (CAS: 13436-58-3)?

2-Methyl-7-nitro-2H-indazole is a crystalline solid with a molecular weight of approximately 213.09 g/mol. It has a melting point of around 188-190°C. The compound is slightly soluble in water but soluble in organic solvents like methanol and ethanol. It exhibits moderate reactivity towards nucleophiles and reducing agents, making it useful in various chemical transformations.

How is 2-Methyl-7-nitro-2H-indazole (CAS: 13436-58-3) typically synthesized?

2-Methyl-7-nitro-2H-indazole is typically synthesized via a nitration process of 2-methyl-2H-indazole. The reaction involves the use of nitric acid in an appropriate solvent at elevated temperatures. The yield is generally good, and the selectivity towards the nitro product is high. Various mild conditions can be employed to improve the reaction kinetics and selectivity.

What industries use 2-Methyl-7-nitro-2H-indazole (CAS: 13436-58-3)?

2-Methyl-7-nitro-2H-indazole is used in the pharmaceutical industry for the synthesis of drug intermediates due to its reactivity and stability. It also finds applications in the sensor industry, particularly in the development of gas sensors, and in the semiconductor industry as a precursor for functional materials. Additionally, it is utilized in polymer synthesis for the development of advanced materials.

What precautions should be taken when handling 2-Methyl-7-nitro-2H-indazole (CAS: 13436-58-3)?

Proper handling of 2-Methyl-7-nitro-2H-indazole requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure to vapors. In case of spillage, it should be handled carefully using appropriate absorbents, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage procedures.