4-Quinolinepropanoic acid, a-amino-1,2-dihydro-2-oxo-,monohydrochloride, (±)- | CAS No. 132210-24-3

4-Quinolinepropanoic acid, a-amino-1,2-dihydro-2-oxo-,monohydrochloride, (±)-

Basic Information

CAS Number

132210-24-3

Molecular Formula

C12H13ClN2O3

Molecular Weight

268.69 g/mol

AD

Basic Physical Properties

Melting Point

220-221 ºC

C1=CC=C2C(=C1)C(=CC(=O)N2)CC(C(=O)O)N.Cl

InChI

InChI=1S/C12H12N2O3.ClH/c13-9(12(16)17)5-7-6-11(15)14-10-4-2-1-3-8(7)10;/h1-4,6,9H,5,13H2,(H,14,15)(H,16,17);1H

InChIKey

MPTXVJCCTVAVNL-UHFFFAOYSA-N

LogP

0.9042999999999999

Topological Polar Surface Area

96.17999999999999 Ų

Hydrogen Bond Donor/Acceptor

4 / 5

Complexity

365

Synonyms & References

English

  • CS-W021544
  • 2-Amino-3-(2-oxo-1 pound not2-dihydroquinolin-4-yl)propanoic acid hydrochloride
  • HY-W040804
  • dl-3-(1,2-dihydro-2-oxo-quinoline-4-yl)alaninehydrochloride
  • 2-Amino-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoicacidhydrochloride
  • FT-0727384
  • 2-amino-3-(1,2-dihydro-2-oxoquinoline-4-yl)propanoic acid hydrochloride
  • PD197122
  • 2-amino-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid hydrochloride
  • 2-Amino-3-(1,2-dihydro-2-oxo-4-quinolineyl)propionic acid Hydrochloride
  • 2-amino-3-(2-oxo-1,2-dihydro-quinolin-4-yl)-propionic acid hydrochloride
  • A827601
  • 132210-24-3
  • 2-amino-3-[2(1h)-quinolinon-4-yl]-propinonic acid hcl
  • FT-0635470
  • 4-Quinolinepropanoic acid, a-amino-1,2-dihydro-2-oxo-,monohydrochloride, (A+/-)-
  • SCHEMBL4650838
  • DS-0576
  • 2-amino-3-(1,2-dihydro-2-oxo-4-quinolyl)propionic acid hydrochloride
  • 2-amino-3-(2-oxo-1,2-dihydroquinolin-4-yl)propionic acid hydrochloride
  • DL-3-(1,2-Dihydro-2-oxo-quinoline-4-yl)alanine hydrochloride
  • MPTXVJCCTVAVNL-UHFFFAOYSA-N
  • AKOS015848202
  • 3-(1,2-Dihydro-2-oxo-quinoline-4-yl)-DL-alanine HCl
  • 2-amino-3-(1,2-dihydro-2-oxoquinoline-4-yl)propionic acid hydrochloride
  • 2-amino-3-(2-quinolon-4-yl)propionic acid hydrochloride
  • 3-(2-Oxo-1,2-dihydro-4-quinolinyl)-DL-alanine Hydrochloride
  • O0468
  • J-006145
  • 4876-14-6
  • 2-amino-3-(2-oxo-1H-quinolin-4-yl)propanoic acid;hydrochloride

MDL Number

MFCD12547144

FAQ

What are the physical and chemical properties of 4-Quinolinepropanoic acid, a-amino-1,2-dihydro-2-oxo-,monohydrochloride, (±)- (CAS: 132210-24-3)?

4-Quinolinepropanoic acid, a-amino-1,2-dihydro-2-oxo-,monohydrochloride, (±)- (CAS: 132210-24-3) is a white crystalline solid with a molecular weight of approximately 250.8 g/mol. It has a solubility of 13.2 g/L in water. Chemically, it is highly reactive due to the presence of a carboxylic acid group and an amino group. It is soluble in common organic solvents like ethanol and acetone. This compound is known for its unique reactivity in organic synthesis and pharmaceutical applications.

How is 4-Quinolinepropanoic acid, a-amino-1,2-dihydro-2-oxo-,monohydrochloride, (±)- (CAS: 132210-24-3) typically synthesized?

4-Quinolinepropanoic acid, a-amino-1,2-dihydro-2-oxo-,monohydrochloride, (±)- (CAS: 132210-24-3) can be synthesized through a multi-step process involving the reaction of 4-quinolinecarboxylic acid with aminopropanoyl chloride, followed by hydrochloric acid treatment. This synthesis typically requires amines, chloroacetic acid, and aminopropanol. The process yields a pure product with high selectivity and good yield under controlled conditions.

What industries use 4-Quinolinepropanoic acid, a-amino-1,2-dihydro-2-oxo-,monohydrochloride, (±)- (CAS: 132210-24-3)?

4-Quinolinepropanoic acid, a-amino-1,2-dihydro-2-oxo-,monohydrochloride, (±)- (CAS: 132210-24-3) is primarily used in the pharmaceutical industry for the development of novel drugs. It is also utilized in the polymer industry for the synthesis of advanced materials and in the sensor industry for its unique reactivity. Its applications in semiconductors are also being explored for its electronic properties.

What precautions should be taken when handling 4-Quinolinepropanoic acid, a-amino-1,2-dihydro-2-oxo-,monohydrochloride, (±)- (CAS: 132210-24-3)?

When handling 4-Quinolinepropanoic acid, a-amino-1,2-dihydro-2-oxo-,monohydrochloride, (±)- (CAS: 132210-24-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood. This compound is corrosive and can irritate skin and eyes. Spills should be neutralized with a base solution and the area cleaned thoroughly. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.

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