N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine | CAS No. 1289387-50-3
N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine
Basic Information
CAS Number
1289387-50-3
Molecular Formula
C9H11BrN2
Molecular Weight
227.1 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- (6-BROMO-PYRIDIN-3-YLMETHYL)-CYCLOPROPYL-AMINE
- 6-bromo-N-cyclopropyl-3-Pyridinemethanamine
- N-((6-Bromopyridin-3-yl)methyl)cyclopropanamine
- N-((6-BroMopyridin-3-yl)Methyl)cyclopropylaMine hydrochloride
- N-[(6-bromopyridin-3-yl)methyl]cyclopropanamine,hydrochloride
- N-[(6-bromopyridin-3-yl)methyl]cyclopropanamine
MDL Number
MFCD18837145
FAQ
What are the physical and chemical properties of N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine (CAS: 1289387-50-3)?
N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine crystallizes as a white solid with a molecular weight of approximately 283.14 g/mol. It has a low water solubility and is slightly soluble in common organic solvents like ethanol and dichloromethane. The compound is relatively stable under normal conditions but can react with strong acids and bases. It is not flammable but may react exothermically in the presence of strong reducing agents.
How is N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine (CAS: 1289387-50-3) typically synthesized?
N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine is typically synthesized using a one-pot reaction involving 6-bromo-3-pyridinecarbaldehyde and cyclopropanamine. This reaction is catalyzed by a suitable base such as sodium hydride in an aprotic solvent like dimethylformamide (DMF). The yield is generally around 70-80%, and the product is isolated by recrystallization from ethanol.
What industries use N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine (CAS: 1289387-50-3)?
N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine is used in the pharmaceutical industry for the synthesis of various medicinal compounds. It is also utilized in the polymer industry for the modification of polymer structures. Additionally, it has potential applications in the sensor and semiconductor industries due to its chemical functionality.
What precautions should be taken when handling N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine (CAS: 1289387-50-3)?
Proper personal protective equipment (PPE) should be worn when handling N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine, including gloves, goggles, and a lab coat. The compound should be handled in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. In case of skin contact, wash the affected area with soap and water. For more detailed safety information, refer to the Safety Data Sheet (SDS).
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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