Compound Q&A
How is N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine (CAS: 1289387-50-3) typically synthesized?
Answer
![N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine](https://static.chemtradehub.com/structs/128/1289387-50-3-fdf9.webp "N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine")
N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine is typically synthesized using a one-pot reaction involving 6-bromo-3-pyridinecarbaldehyde and cyclopropanamine. This reaction is catalyzed by a suitable base such as sodium hydride in an aprotic solvent like dimethylformamide (DMF). The yield is generally around 70-80%, and the product is isolated by recrystallization from ethanol.
About
CAS No
1289387-50-3
English Name
N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine
Molecular Formula
C9H11BrN2
Molecular Weight
227.1 g/mol
SMILES
c1cc(ncc1CNC2CC2)Br
InChIKey
AUEORDKZYQTMJT-UHFFFAOYSA-N
Last Updated: 2026-03-11 04:00
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