N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine(CAS: 1289387-50-3)

N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine crystallizes as a white solid with a molecular weight of approximately 283.14 g/mol. It has a low water solubility and is slightly soluble in common organic solvents like ethanol and dichloromethane. The compound is relatively stable under normal conditions but can react with strong acids and bases. It is not flammable but may react exothermically in the presence of strong reducing agents.

N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine is typically synthesized using a one-pot reaction involving 6-bromo-3-pyridinecarbaldehyde and cyclopropanamine. This reaction is catalyzed by a suitable base such as sodium hydride in an aprotic solvent like dimethylformamide (DMF). The yield is generally around 70-80%, and the product is isolated by recrystallization from ethanol.

N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine is used in the pharmaceutical industry for the synthesis of various medicinal compounds. It is also utilized in the polymer industry for the modification of polymer structures. Additionally, it has potential applications in the sensor and semiconductor industries due to its chemical functionality.

Proper personal protective equipment (PPE) should be worn when handling N-[(6-Bromo-3-pyridinyl)methyl]cyclopropanamine, including gloves, goggles, and a lab coat. The compound should be handled in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. In case of skin contact, wash the affected area with soap and water. For more detailed safety information, refer to the Safety Data Sheet (SDS).