(2Z)-(2-Amino-1,3-thiazol-4-yl)[(trityloxy)imino]acetic acid | CAS No. 128438-01-7

(2Z)-(2-Amino-1,3-thiazol-4-yl)[(trityloxy)imino]acetic acid

Basic Information

CAS Number

128438-01-7

Molecular Formula

C24H19N3O3S

Molecular Weight

429.5 g/mol

AD

Basic Physical Properties

C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)ON=C(C4=CSC(=N4)N)C(=O)O

InChI

InChI=1S/C24H19N3O3S/c25-23-26-20(16-31-23)21(22(28)29)27-30-24(17-10-4-1-5-11-17,18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-16H,(H2,25,26)(H,28,29)/b27-21-

InChIKey

XEZIFGWTSLOMMT-MEFGMAGPSA-N

LogP

4.522700000000004

Topological Polar Surface Area

97.8 Ų

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

580

Synonyms & References

English

  • (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-trityloxyiminoacetic acid
  • AKOS015900616
  • xyimino]-acetic acid
  • AC-5568
  • A805820
  • MFCD08458707
  • 128438-01-7
  • (Z)-2-(2-Aminothiazol-4-yl)-2-((trityloxy)imino)acetic acid
  • SCHEMBL1525781
  • AS-12966
  • (Z)-2-(2-Aminothiazol-4-yl)-2-((trityloxy)imino)aceticacid
  • 4-Thiazoleacetic acid, 2-amino-alpha-[(triphenylmethoxy)imino]-, (alphaZ)-
  • 2-(2-aminothiazol-4-yl)-2-tritylimino-acetic acid
  • (z)-2-(2-aminothiazole-4-yl-)-2-trityloxyimino acetic acid
  • (2-Amino-thiazol-4-yl)-[(Z)-tritylo
  • AM91530
  • (Z)-2-(2-Aminothiazol-4-yl)-2-trityloxyiminoacetic acid
  • ATOA
  • ( Z )-2-(2-AMINOTHIAZOL-4-YL)-2-TRITYLOXYIMINOACETIC ACID (ATOA)
  • (Z)-2-(2-Aminothiazole-4-yl-)-2-trityloxyimino acetic acid
  • AT-TOA
  • 4-Thiazoleaceticacid, 2-amino-a-[(triphenylmethoxy)imino]-,(Z)-
  • (Z)-2-(2-Aminothiazol-4-yl)-2-(trityloxy)iminoacetic acid
  • 2-(2-Amino-4-thiazolyl)-2-[(Z)-(trityloxy)imino]acetic acid
  • (Z)-2-(2-aminothiazol-4-yl)-2-trityliminoacetic acid
  • (2-AMino-thiazol-4-yl)-[(Z)-tritylo xyiMino]-acetic acid
  • (Z)-2-(2-AMINOTHIAZOLE-4-YL)-2-TRITYLOXYIMINO ACETIC ACID
  • ATTAA:(Z)-2-(2-AMINOTHIAZOL-4-YL)-2-TRITYLOXYIMINOACETIC ACID
  • ( Z )-2-(2-aminothiazol-4-yl)-2-trityloxyiminoacetic Acid (AT-TOA)

MDL Number

MFCD08458707

Customs Code

2934100090

FAQ

What are the physical and chemical properties of (2Z)-(2-Amino-1,3-thiazol-4-yl)[(trityloxy)imino]acetic acid (CAS: 128438-01-7)?

The compound (2Z)-(2-Amino-1,3-thiazol-4-yl)[(trityloxy)imino]acetic acid is a white crystalline solid with a molecular weight of approximately 451.4 g/mol. It has a pKa of about 7.6 and is moderately soluble in water. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It does not show strong volatility or flammability under normal conditions.

How is (2Z)-(2-Amino-1,3-thiazol-4-yl)[(trityloxy)imino]acetic acid (CAS: 128438-01-7) typically synthesized?

This compound is typically synthesized by the amidation of trityloxyacetic acid with 2-amino-1,3-thiazol-4-ylamine. The reaction usually requires an appropriate catalyst and can be performed in a polar aprotic solvent. The yield is generally good, and the product can be purified by recrystallization or column chromatography.

What industries use (2Z)-(2-Amino-1,3-thiazol-4-yl)[(trityloxy)imino]acetic acid (CAS: 128438-01-7)?

This compound is primarily used in the pharmaceutical industry for the synthesis of various bioactive molecules. It also finds applications in the polymer industry for the modification of polymers and in the semiconductor industry for the development of organic electronic devices.

What precautions should be taken when handling (2Z)-(2-Amino-1,3-thiazol-4-yl)[(trityloxy)imino]acetic acid (CAS: 128438-01-7)?

Proper personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn when handling this compound. It should be stored in a cool, dry place away from direct sunlight and sources of ignition. In case of spill, it should be handled using appropriate spill response protocols, and the Material Safety Data Sheet (MSDS) should be consulted for specific guidelines.

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