Sennoside B | CAS No. 128-57-4

Sennoside B

Basic Information

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CAS Number

128-57-4

Molecular Formula

C42H38O20

Molecular Weight

862.74 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Yellow powder

Melting Point

209～212℃

Boiling Point

698.48°C (rough estimate)

Flash Point

348.6°C

Solubility

1e+006 mg/L @ 25 °C (est)

Refractive Index

1.7630 (estimate)

Specific Rotation

D20 -100° (c = 0.2 in 70% acetone); D20 -67° (c = 0.4 in 70% dioxane)

SMILES

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OC[C@H]1O[C@@H](Oc2cccc3c2C(=O)c2c([C@@H]3[C@@H]3c4cc(cc(c4C(=O)c4c3cccc4O[C@@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O)O)C(=O)O)cc(cc2O)C(=O)O)[C@@H]([C@H]([C@@H]1O)O)O

InChI

InChI=1S/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25-,26+,31-,32-,35+,36+,37-,38-,41-,42-/m1/s1

InChIKey

IPQVTOJGNYVQEO-AIFLABODSA-N

LogP

-1.0956000000000001

Topological Polar Surface Area

347.96000000000004 Å²

Hydrogen Bond Donor/Acceptor

12 / 20

Complexity

1550

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Storage Conditions

-20℃

Synonyms & References

English

sennoside B
[9,9'-Bianthracene]-2,2'-dicarboxylicacid, 5,5'-bis(b-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-,(9R,9'S)-
PURSENNIDE
SENNOSIDE B(AS) PrintBack
(9S)-9-[(9R)-2-Carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)ox
(9S)-9-[(9R)-2-Carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid
[ "" ]
Tisasen B
GLYSENNIDE
SENNOSIDE B(P)
SENNIDINE B(RG)
SENNOSIDE B(SH)
Sennoside B std.
SENNOSIDE B hplc
Sennoside B ,98%
Sennoside-B
MLS002473001
F887D1637W
SMR001397106
C42H38O20
NSC112930
SENNOSIDE B (SENNA)
cid_91440
BDBM80739
Sennoside B (6CI,7CI,8CI)
HMS2226P04
s4018
LMPK13040017
ST075008
O916
N1677

MDL Number

MFCD00151528

FAQ

What is Sennoside B (CAS: 128-57-4)?

Sennoside B is a natural anthraquinone glycoside derived from the Senna plant genus. Its chemical formula is C19H18O10, and it is known for its mild laxative properties. It is a yellowish solid with a bitter taste, commonly used in pharmaceuticals for its pharmacological effects. CAS 128-57-4 identifies this compound as a key active ingredient in herbal remedies.

What are the main uses of Sennoside B (CAS: 128-57-4)?

Sennoside B (CAS 128-57-4) is primarily used as a laxative in over-the-counter medications for constipation relief. It also serves as a research compound in studies related to gastrointestinal motility and as a reference material in pharmaceutical development. Its natural origin makes it valuable in herbal medicine formulations.

Is Sennoside B (CAS: 128-57-4) safe?

Sennoside B is generally safe when used as directed, but excessive use may cause dehydration or electrolyte imbalances. It is considered low in toxicity for short-term use, though skin and eye irritation can occur during handling. Safety standards ensure it meets regulatory guidelines for pharmaceutical applications, including FDA approval for laxative use.

How should Sennoside B (CAS: 128-57-4) be stored?

Sennoside B should be stored in a cool, dry place away from light to maintain stability. It is best kept in a sealed, airtight container to prevent degradation. Storage conditions should avoid high humidity and temperature fluctuations. Proper labeling and adherence to safety standards are essential for handling CAS 128-57-4.