(9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1) | CAS No. 125-69-9

(9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1)

Basic Information

CAS Number

125-69-9

Molecular Formula

C18H26BrNO

Molecular Weight

352.32 g/mol

AD

Basic Physical Properties

Melting Point

125-127℃

Water Solubility

Soluble in water (40 mM), and alcohol (1:10).

Specific Rotation

D20 +27.6° (c = 1.5 in water)

CN1CCC23CCCCC2C1CC4=C3C=C(C=C4)OC.Br

InChI

InChI=1S/C18H25NO.BrH/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H/t15-,17+,18+;/m1./s1

InChIKey

MISZALMBODQYFT-URVXVIKDSA-N

LogP

3.9613000000000036

Topological Polar Surface Area

12.47 Ų

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

370

Safety Information

View Safety Information

Hazard Class

Class 6.1(b) Class 6.1(b)

Synonyms & References

English

  • Dextrometorphan hydrobromide
  • Bayer Select Flu Relief
  • Contac Cough & Sore Throat Formula
  • Viro-Med
  • Dormetan
  • Childrens Robitussin 12 Hour Cough Relief
  • Demorphine
  • Dextromethorphan Polistirex Extended Release
  • Robitussin Pediatric Cough & Cold
  • Trind-DM
  • AVP-923 COMPONENT DEXTROMETHORPHAN HYDROBROMIDE
  • Dextroramin P
  • Robitussin Maximum Strength Cough
  • Demorphan
  • Contac Severe Cold Formula Maximum Strength
  • Ro 1-5470
  • Tylenol Children's Cough Cold Chewable Tablets
  • (9?,13?,14?)-3-Methoxy-17-methylmorphinan hydrobromide
  • MORPHINAN, 3-METHOXY-17-METHYL-, (9alpha,13alpha,14alpha)-, HBR
  • Cough Gels
  • Canfodion
  • Equaline Tussin Cough
  • Tusilan
  • Leader CoughDM
  • NUEDEXTA COMPONENT DEXTROMETHORPHAN HYDROBROMIDE
  • Delsym
  • 3-METHOXY-17-METHYL-9alpha,13alpha,14alpha-MORPHINAN HYDROBROMIDE
  • Childrens Robitussin Cough Long-acting
  • Delsym Cough
  • VicksFormula 44 Cough
  • DEXTROMETHORPHAN HYDROBROMIDE [MI]

Customs Code

2939190090

FAQ

What are the physical and chemical properties of (9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1) (CAS: 125-69-9)?

(9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1) is a crystalline compound with a molecular weight of approximately 446.33 g/mol. It has a high solubility in water and moderate solubility in organic solvents. Chemically, it is stable under normal conditions but may react with strong bases. It is commonly found in pharmaceutical applications.

How is (9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1) (CAS: 125-69-9) typically synthesized?

(9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1) is synthesized through the bromination of 3-methoxy-17-methylmorphinan, followed by a reaction with an appropriate base. Common catalysts include sodium hydride, and the reaction is typically carried out in anhydrous solvents like dimethylformamide (DMF) to achieve high yield and selectivity.

What industries use (9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1) (CAS: 125-69-9)?

(9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1) is primarily used in the pharmaceutical industry for the production of analgesic and antitussive medications. It is also of interest in the research and development of new drugs and formulations.

What precautions should be taken when handling (9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1) (CAS: 125-69-9)?

When handling (9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. In case of a spill, immediately clean the area using appropriate absorbents and follow the safety data sheet (SDS) guidelines for disposal. This compound should be stored in a cool, dry place, away from heat sources and incompatible materials.

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