Compound Q&A

How is (9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1) (CAS: 125-69-9) typically synthesized?

Answer

(9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1)
(9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1) is synthesized through the bromination of 3-methoxy-17-methylmorphinan, followed by a reaction with an appropriate base. Common catalysts include sodium hydride, and the reaction is typically carried out in anhydrous solvents like dimethylformamide (DMF) to achieve high yield and selectivity.

About

CAS No 125-69-9
English Name (9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1)
Molecular Formula C18H26BrNO
Molecular Weight 352.32 g/mol
SMILES CN1CCC23CCCCC2C1CC4=C3C=C(C=C4)OC.Br
InChIKey MISZALMBODQYFT-URVXVIKDSA-N
Last Updated: 2025-10-08 00:58

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