(9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1)(CAS: 125-69-9)

(9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1) is a crystalline compound with a molecular weight of approximately 446.33 g/mol. It has a high solubility in water and moderate solubility in organic solvents. Chemically, it is stable under normal conditions but may react with strong bases. It is commonly found in pharmaceutical applications.

(9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1) is synthesized through the bromination of 3-methoxy-17-methylmorphinan, followed by a reaction with an appropriate base. Common catalysts include sodium hydride, and the reaction is typically carried out in anhydrous solvents like dimethylformamide (DMF) to achieve high yield and selectivity.

(9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1) is primarily used in the pharmaceutical industry for the production of analgesic and antitussive medications. It is also of interest in the research and development of new drugs and formulations.

When handling (9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan hydrobromide (1:1), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. In case of a spill, immediately clean the area using appropriate absorbents and follow the safety data sheet (SDS) guidelines for disposal. This compound should be stored in a cool, dry place, away from heat sources and incompatible materials.