2-[(1R)-1-Aminoethyl]-4-fluorophenol

Basic Information

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CAS Number

1228570-33-9

Molecular Formula

C8H10FNO

Molecular Weight

155.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

SMILES

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C[C@@H](N)c1cc(F)ccc1O

InChI

InChI=1S/C8H10FNO/c1-5(10)7-4-6(9)2-3-8(7)11/h2-5,11H,10H2,1H3/t5-/m1/s1

InChIKey

SSNRPTHWRFURQQ-RXMQYKEDSA-N

LogP

1.551

Topological Polar Surface Area

46.25 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

131

Synonyms & References

English

2-(1-aminoethyl)-4-fluorophenol
2-(1-AMINOETHYL)-4-FLUOROPHENOL HCL
2-[(1R)-1-aminoethyl]-4-fluoro-phenol

MDL Number

MFCD06761863

FAQ

What are the physical and chemical properties of 2-[(1R)-1-Aminoethyl]-4-fluorophenol (CAS: 1228570-33-9)?

2-[(1R)-1-Aminoethyl]-4-fluorophenol is a white crystalline solid with a molecular weight of approximately 216.16 g/mol. It is sparingly soluble in water and ethanol. Chemically, it reacts with bases and is used in the synthesis of other compounds. It is stable under normal conditions but should be stored in a closed container to prevent degradation.

How is 2-[(1R)-1-Aminoethyl]-4-fluorophenol (CAS: 1228570-33-9) typically synthesized?

2-[(1R)-1-Aminoethyl]-4-fluorophenol is typically synthesized by the hydrogenation of 4-fluorophenylacetaldehyde with a catalyst such as palladium on carbon under hydrogen pressure. This method provides a high yield and good selectivity. The reaction is conducted in the presence of a base like sodium hydroxide in an aqueous solvent.

What industries use 2-[(1R)-1-Aminoethyl]-4-fluorophenol (CAS: 1228570-33-9)?

2-[(1R)-1-Aminoethyl]-4-fluorophenol is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for the preparation of functional polymers. Additionally, it finds applications in the sensor and semiconductor industries due to its unique chemical properties.

What precautions should be taken when handling 2-[(1R)-1-Aminoethyl]-4-fluorophenol (CAS: 1228570-33-9)?

When handling 2-[(1R)-1-Aminoethyl]-4-fluorophenol, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. In case of a spill, it should be promptly cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.