Compound Q&A

How is 2-[(1R)-1-Aminoethyl]-4-fluorophenol (CAS: 1228570-33-9) typically synthesized?

Answer

2-[(1R)-1-Aminoethyl]-4-fluorophenol
2-[(1R)-1-Aminoethyl]-4-fluorophenol is typically synthesized by the hydrogenation of 4-fluorophenylacetaldehyde with a catalyst such as palladium on carbon under hydrogen pressure. This method provides a high yield and good selectivity. The reaction is conducted in the presence of a base like sodium hydroxide in an aqueous solvent.

About

English Name 2-[(1R)-1-Aminoethyl]-4-fluorophenol
Molecular Formula C8H10FNO
Molecular Weight 155.17 g/mol
SMILES C[C@@H](N)c1cc(F)ccc1O
InChIKey SSNRPTHWRFURQQ-RXMQYKEDSA-N
Last Updated: 2026-03-11 04:00

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