2-[(1R)-1-Aminoethyl]-4-fluorophenol(CAS: 1228570-33-9)

2-[(1R)-1-Aminoethyl]-4-fluorophenol is a white crystalline solid with a molecular weight of approximately 216.16 g/mol. It is sparingly soluble in water and ethanol. Chemically, it reacts with bases and is used in the synthesis of other compounds. It is stable under normal conditions but should be stored in a closed container to prevent degradation.

2-[(1R)-1-Aminoethyl]-4-fluorophenol is typically synthesized by the hydrogenation of 4-fluorophenylacetaldehyde with a catalyst such as palladium on carbon under hydrogen pressure. This method provides a high yield and good selectivity. The reaction is conducted in the presence of a base like sodium hydroxide in an aqueous solvent.

2-[(1R)-1-Aminoethyl]-4-fluorophenol is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for the preparation of functional polymers. Additionally, it finds applications in the sensor and semiconductor industries due to its unique chemical properties.

When handling 2-[(1R)-1-Aminoethyl]-4-fluorophenol, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. In case of a spill, it should be promptly cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.