2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine

Basic Information

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CAS Number

122368-54-1

Molecular Formula

C17H19ClN2O

Molecular Weight

302.81 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

421.7°C at 760 mmHg

SMILES

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C1CNCCC1OC(C2=CC=C(C=C2)Cl)C3=CC=CC=N3

InChI

InChI=1S/C17H19ClN2O/c18-14-6-4-13(5-7-14)17(16-3-1-2-10-20-16)21-15-8-11-19-12-9-15/h1-7,10,15,17,19H,8-9,11-12H2

InChIKey

OTZYADIPHOGUDN-UHFFFAOYSA-N

LogP

3.5930000000000017

Topological Polar Surface Area

34.15 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

301

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

AC-24024
Pyridine, 2-[(4-chlorophenyl)(4-piperidinyloxy)methyl]-
2-[(S)-(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine
Chlorophenyl)(piperidin-4-yloxy)methyl)pyridine
4-[(4-chlorophenyl)-2-pyridylmethoxy]piperidine
MFCD13184723
SB44353
OTZYADIPHOGUDN-UHFFFAOYSA-N
A804882
SB41046
AKOS015918327
FT-0659219
(+/-)-4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidine
122368-54-1
BCP12927
SY103487
2-[(4-chlorophenyl)-piperidin-4-yloxymethyl]pyridine
Pyridine,2-[(4-chlorophenyl)(4-piperidinyloxy)methyl]-
DTXSID90456739
SCHEMBL1499960
2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine
2-{(4-Chlorophenyl)[(piperidin-4-yl)oxy]methyl}pyridine
AS-20124
(+/-)-4-[(4-chlorophenyl)(2-pyridyl)-methoxy]piperidine
(R,S)-4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidine
C11183
4-[1-(4-chlorophenyl)-1-(2-pyridyl)methoxy]piperidine
CS-B0347
2-((4-chlorophenyl)(piperidin-4-yloxy)methyl)pyridine
2-[(4-Chlorophenyl)(4-piperidyloxy)methyl]pyridine
2-((4-Chlorophenyl)(piperidin-4-yloxy)methyl)pyridine

MDL Number

MFCD13184723

FAQ

What are the physical and chemical properties of 2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine (CAS: 122368-54-1)?

2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine is a solid compound with a crystalline form. Its molecular weight is approximately 341.22 g/mol. It has a low solubility in water but is slightly soluble in organic solvents. The compound exhibits basic properties due to the piperidino group. It is reactive towards acidic conditions and can undergo substitution reactions. The compound is not flammable but should be handled with care due to its basic nature.

How is 2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine (CAS: 122368-54-1) typically synthesized?

2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine is typically synthesized through a multistep process involving the coupling of 4-chloroaniline with 4-piperidinol, followed by a functional group transformation using a piperidine derivative. The synthesis involves the use of catalysts such as triphenylphosphine and an appropriate coupling reagent. The overall yield is moderate, and the method provides good selectivity for the target compound.

What industries use 2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine (CAS: 122368-54-1)?

2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine is used in the pharmaceutical industry for its potential therapeutic applications. It may serve as a precursor or a component in the development of new drugs. Additionally, it finds limited use in the polymer industry for modifying polymer properties and in sensor technology for its ability to interact with certain analytes.

What precautions should be taken when handling 2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine (CAS: 122368-54-1)?

When handling 2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine, it is recommended to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a fume hood to avoid inhalation exposure. Spills should be immediately contained and cleaned up using appropriate absorbent materials. The material safety data sheet (MSDS) should be consulted for detailed safety information. The compound is not considered highly toxic but should be handled with care due to its basic nature and potential for skin irritation.