2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine(CAS: 122368-54-1)

2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine is a solid compound with a crystalline form. Its molecular weight is approximately 341.22 g/mol. It has a low solubility in water but is slightly soluble in organic solvents. The compound exhibits basic properties due to the piperidino group. It is reactive towards acidic conditions and can undergo substitution reactions. The compound is not flammable but should be handled with care due to its basic nature.

2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine is typically synthesized through a multistep process involving the coupling of 4-chloroaniline with 4-piperidinol, followed by a functional group transformation using a piperidine derivative. The synthesis involves the use of catalysts such as triphenylphosphine and an appropriate coupling reagent. The overall yield is moderate, and the method provides good selectivity for the target compound.

2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine is used in the pharmaceutical industry for its potential therapeutic applications. It may serve as a precursor or a component in the development of new drugs. Additionally, it finds limited use in the polymer industry for modifying polymer properties and in sensor technology for its ability to interact with certain analytes.

When handling 2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine, it is recommended to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a fume hood to avoid inhalation exposure. Spills should be immediately contained and cleaned up using appropriate absorbent materials. The material safety data sheet (MSDS) should be consulted for detailed safety information. The compound is not considered highly toxic but should be handled with care due to its basic nature and potential for skin irritation.