1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride | CAS No. 121-25-5

1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride

Basic Information

CAS Number

121-25-5

Molecular Formula

C14H19ClN4

Molecular Weight

243.33 g/mol

AD

Basic Physical Properties

Boiling Point

°Cat760mmHg

Flash Point

°Cat760mmHg

CCCc1ncc(c(n1)N)C[n+]2ccccc2C.[Cl-]

InChI

InChI=1S/C14H19N4.ClH/c1-3-6-13-16-9-12(14(15)17-13)10-18-8-5-4-7-11(18)2;/h4-5,7-9H,3,6,10H2,1-2H3,(H2,15,16,17);1H/q+1;/p-1

InChIKey

LCTXBFGHZLGBNU-UHFFFAOYSA-M

LogP

-0.75930

Complexity

246

Safety Information

View Safety Information

Stability

Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.

Synonyms & References

English

  • amprolium
  • Amprolium [INN:BAN]
  • 1-((4-Amino-2-propyl-5-pyrimidinyl)methyl)-2-methylpyridinium chloride
  • 1-((4-Amino-2-propyl-5-pyrimidinyl)methyl)-2-picolinium chloride
  • Amprol, Veterinary
  • Amprolio
  • Amprolio [INN-Spanish]
  • Amprolium [INN-Latin]
  • Amprovine
  • 2-Picolinium, 1-((4-amino-2-propyl-5-pyrimidinyl)methyl)-, chloride
  • Pyridinium, 1-((4-amino-2-propyl-5-pyrimidinyl)methyl)-2-methyl-, chloride
  • 1-[(4-amino-2-propylpyrimidin-5-yl)methyl]-2-methylpyridinium chloride
  • AMPROLIUM HCL
  • (1-(4-AMINO-2-PROPYL-5-PYRIMIDINYL)-METHYL)-2-METHYLPYRID.
  • 1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride
  • 5-[(2-methylpyridin-1-ium-1-yl)methyl]-2-propylpyrimidin-4-amine chloride
  • AMPROLIUM USP 26,BPV 98
  • AMproliuM,USP
  • Pyridinium,1-(4-amino-2-propyl-5-pyrimidinyl)methyl-2-methyl-,chloride
  • 5-[(2-methylpyridin-1-ium-1-yl)methyl]-2-propyl-pyrimidin-4-amine chloride
  • AMproliuM, USP
  • AMPROLIUM USP 26, BPV 98
  • Pyridinium, 1-(4-amino-2-propyl-5-pyrimidinyl)methyl-2-methyl-, chloride

MDL Number

MFCD00072061

FAQ

What are the physical and chemical properties of 1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride (CAS: 121-25-5)?

1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride (CAS: 121-25-5) is a crystalline solid with a molecular weight of approximately 315.36 g/mol. It has a high solubility in water and moderate solubility in organic solvents. This compound is known to be chemically stable under normal conditions, but it reacts with strong bases and acids. It is often used in synthetic applications due to its reactivity and specific functional groups.

How is 1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride (CAS: 121-25-5) typically synthesized?

1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride (CAS: 121-25-5) is typically synthesized via a multi-step process involving the coupling of a pyrimidine derivative with a 2-methylpyridinium ion. Commonly, this involves the use of a base like sodium hydride and a coupling reagent such as HATU. The reaction yields a highly functionalized compound with good selectivity and moderate to high yields.

What industries use 1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride (CAS: 121-25-5)?

1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride (CAS: 121-25-5) is primarily used in the pharmaceutical industry for its biological activity and potential as a drug candidate. It is also explored in the semiconductors industry for its electronic properties. Additionally, it has applications in the development of sensors due to its reactivity and specific functional groups.

What precautions should be taken when handling 1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride (CAS: 121-25-5)?

When handling 1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride (CAS: 121-25-5), it is important to wear appropriate personal protective equipment (PPE), including gloves and goggles. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbents, and the area should be decontaminated. Always consult the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.

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