3-Amino-N-isopropylbenzenesulfonamide

Basic Information

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CAS Number

118837-66-4

Molecular Formula

C9H14N2O2S

Molecular Weight

214.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

384 ℃ at 760 mmHg

SMILES

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CC(C)NS(=O)(=O)C1=CC=CC(=C1)N

InChI

InChI=1S/C9H14N2O2S/c1-7(2)11-14(12,13)9-5-3-4-8(10)6-9/h3-7,11H,10H2,1-2H3

InChIKey

NIUZLEBXTLRCKA-UHFFFAOYSA-N

LogP

0.9555

Topological Polar Surface Area

72.19 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

269

Safety Information

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Hazard Statement

Synonyms & References

English

A892809
SY028836
3-Amino-N-isopropylbenzenesulphonamide
N-Isopropyl-3-aminobenzenesulfonamide
118837-66-4
SB79150
AKOS000145699
CS-0211125
MFCD09027278
3-Amino-N-isopropylbenzenesulfonamide
3-amino-N-propan-2-ylbenzenesulfonamide
FT-0755085
SCHEMBL3649156
AC3144
3-Amino-N-(propan-2-yl)benzene-1-sulfonamide
Benzenesulfonamide,3-amino-N-(1-methylethyl)-
3-amino-N-isopropyl-benzenesulfonamide
N-Isopropyl 3-aminobenzenesulfonamide
NIUZLEBXTLRCKA-UHFFFAOYSA-N
BS-25995
DTXSID00588575
3-Amino-N-(prop-2-yl)benzenesulphonamide, 3-(N-Isopropylsulphamoyl)aniline

MDL Number

MFCD09027278

Customs Code

2935009090

FAQ

What are the physical and chemical properties of 3-Amino-N-isopropylbenzenesulfonamide (CAS: 118837-66-4)?

3-Amino-N-isopropylbenzenesulfonamide is a crystalline compound with a molecular weight of approximately 258.36 g/mol. It has a solubility of about 1.5 g/100 mL in water. Chemically, it is less reactive compared to other sulfonamides but can undergo typical sulfonamide reactions such as amidation and esterification. It is slightly soluble in common organic solvents like ethanol and acetone.

How is 3-Amino-N-isopropylbenzenesulfonamide (CAS: 118837-66-4) typically synthesized?

3-Amino-N-isopropylbenzenesulfonamide can be synthesized through a multi-step process. The initial step involves the preparation of the corresponding sulfonamide from the appropriate aromatic amine and isopropylbenzenesulfonyl chloride, followed by substitution reactions. Commonly, this is achieved using a catalytic amount of a suitable base like triethylamine in a suitable solvent such as dichloromethane or acetonitrile. The yield is typically around 80-85%.

What industries use 3-Amino-N-isopropylbenzenesulfonamide (CAS: 118837-66-4)?

3-Amino-N-isopropylbenzenesulfonamide (CAS: 118837-66-4) finds applications in the pharmaceutical industry, where it can be used as an intermediate in the synthesis of various drugs. It is also utilized in the polymer industry for the modification of materials, and in the development of sensors due to its unique chemical properties. Additionally, it can be used in the semiconductor industry for specific applications in material science and electronics.

What precautions should be taken when handling 3-Amino-N-isopropylbenzenesulfonamide (CAS: 118837-66-4)?

When handling 3-Amino-N-isopropylbenzenesulfonamide, it is important to wear protective equipment such as gloves, goggles, and a lab coat to prevent skin and eye contact. Work in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed emergency procedures and handling instructions.