Compound Q&A

How is 3-Amino-N-isopropylbenzenesulfonamide (CAS: 118837-66-4) typically synthesized?

Answer

3-Amino-N-isopropylbenzenesulfonamide
3-Amino-N-isopropylbenzenesulfonamide can be synthesized through a multi-step process. The initial step involves the preparation of the corresponding sulfonamide from the appropriate aromatic amine and isopropylbenzenesulfonyl chloride, followed by substitution reactions. Commonly, this is achieved using a catalytic amount of a suitable base like triethylamine in a suitable solvent such as dichloromethane or acetonitrile. The yield is typically around 80-85%.

About

English Name 3-Amino-N-isopropylbenzenesulfonamide
Molecular Formula C9H14N2O2S
Molecular Weight 214.29 g/mol
SMILES CC(C)NS(=O)(=O)C1=CC=CC(=C1)N
InChIKey NIUZLEBXTLRCKA-UHFFFAOYSA-N
Last Updated: 2025-12-25 08:48

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