![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
Methyl 2-methyl-2-[4-(2-{[(4-methylphenyl)sulfonyl]oxy}ethyl)phenyl]propanoate | CAS No. 1181267-30-0
Methyl 2-methyl-2-[4-(2-{[(4-methylphenyl)sulfonyl]oxy}ethyl)phenyl]propanoate
Basic Information
CAS Number
1181267-30-0
Molecular Formula
C20H24O5S
Molecular Weight
376.47 g/mol
AD
Basic Physical Properties
Solubility
Insuluble (6.0E-3 g/L) (25 ºC),
Synonyms & References
English
- Bilastine ITS-2
- 2-methyl-2-{4-[2-(toluene-4-sulfonyloxy)-ethyl]-phenyl}-propionic acid methylester
- Methyl 2-methyl-2-(4-(2-(tosyloxy)ethyl)phenyl)propanoate
- methyl 2-methyl-2-[4-[2-(4-methylphenyl)sulfonyloxyethyl]phenyl]propanoate
- alpha,alpha-Dimethyl-4-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]benzeneacetic acid methyl ester
MDL Number
MFCD30342444
FAQ
What are the physical and chemical properties of Methyl 2-methyl-2-[4-(2-{[(4-methylphenyl)sulfonyl]oxy}ethyl)phenyl]propanoate (CAS: 1181267-30-0)?
The compound is a crystalline solid with a molecular weight of approximately 414.47 g/mol. It has limited water solubility and is poorly soluble in common organic solvents. Chemically, it is relatively stable but can react with strong bases. Its reactivity is moderate, and it shows good selectivity in specific organic transformations.
How is Methyl 2-methyl-2-[4-(2-{[(4-methylphenyl)sulfonyl]oxy}ethyl)phenyl]propanoate (CAS: 1181267-30-0) typically synthesized?
The compound is typically synthesized through a multi-step process involving the coupling of a sulfonyl chloride with a substituted phenol. The reaction is catalyzed by a phase-transfer catalyst, and the product is isolated through column chromatography. The yield is moderate, around 70%, and the reaction is selective for the desired product.
What industries use Methyl 2-methyl-2-[4-(2-{[(4-methylphenyl)sulfonyl]oxy}ethyl)phenyl]propanoate (CAS: 1181267-30-0)?
This compound is primarily used in the pharmaceutical industry for its potential as a precursor in the synthesis of various drugs. It also has applications in the chemical industry, particularly in the development of functional materials such as sensors and semiconductors.
What precautions should be taken when handling Methyl 2-methyl-2-[4-(2-{[(4-methylphenyl)sulfonyl]oxy}ethyl)phenyl]propanoate (CAS: 1181267-30-0)?
When handling this compound, it is crucial to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to prevent inhalation. Spills should be promptly cleaned up with appropriate absorbents, and the SDS (Safety Data Sheet) should be consulted for detailed instructions. Ensure proper storage in a dry, cool place, away from incompatible materials.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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