Compound Q&A
How is 5-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-fluorobenzaldehyde (CAS: 113984-67-1) typically synthesized?
Answer
![5-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-fluorobenzaldehyde](https://static.chemtradehub.com/structs/113/113984-67-1-936e.webp "5-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-fluorobenzaldehyde")
5-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-fluorobenzaldehyde is typically synthesized through a silylation reaction of 2-fluorobenzaldehyde with dimethyl(2-methyl-2-propanyl)silyl chloride in the presence of a base such as imidazole. The reaction is carried out under anhydrous conditions to avoid hydrolysis. The yield is generally high, and the product shows good selectivity towards the desired silyl ether functionality.
About
CAS No
113984-67-1
English Name
5-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-fluorobenzaldehyde
Molecular Formula
C13H19FO2Si
Molecular Weight
254.38 g/mol
SMILES
CC(C)(C)[Si](C)(C)Oc1ccc(c(c1)C=O)F
InChIKey
LCRGCKGCZUAUDG-UHFFFAOYSA-N
Last Updated: 2026-04-02 10:24
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