2-(Chloromethyl)-4-methylquinazoline

Basic Information

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CAS Number

109113-72-6

Molecular Formula

C10H9ClN2

Molecular Weight

192.65 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Powder

Melting Point

61.0 to 65.0 deg-C

Boiling Point

240°C at 760 mmHg

SMILES

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CC1=NC(=NC2=CC=CC=C12)CCl

InChI

InChI=1S/C10H9ClN2/c1-7-8-4-2-3-5-9(8)13-10(6-11)12-7/h2-5H,6H2,1H3

InChIKey

UHCUBOJGMLASBY-UHFFFAOYSA-N

LogP

2.6770200000000006

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

174

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

SY020590
AMY309
2-chloromethyl-4-methyl-quinazoline
KC7BTH55VT
SCHEMBL637147
CS-M2666
AKOS000165603
2-(chloromethyl)-4-methylquinazoline
UHCUBOJGMLASBY-UHFFFAOYSA-N
DTXSID40287111
(4-methyl-quinazolin-2-yl)-methylchloride
NS00077867
Quinazoline, 2-(chloromethyl)-4-methyl-
2-(chloromethyl)-4-methyl-quinazoline
AC-26252
GS-3878
109113-72-6
UNII-KC7BTH55VT
A1-00286
J-506297
2-CHLOROMETHYL-4-METHYLQUINAZOLINE
EN300-29653
SB17650
Quinazoline, 2-(chloromethyl)-4-methyl-; 2-(chloromethyl)-4-methyl-quinazoline
C2928
FT-0697295
NSC48971
NSC-48971
2-(chloromethyl)-4-methylquizoline
BCP04760
MFCD09807547

MDL Number

MFCD09807547

Customs Code

2933499090

FAQ

What is 2-(Chloromethyl)-4-methylquinazoline (CAS: 109113-72-6)?

2-(Chloromethyl)-4-methylquinazoline (CAS: 109113-72-6) is a synthetic organic compound with the molecular formula C12H9ClN2. It belongs to the quinazoline family, known for its biological activity and applications in medicinal chemistry. The compound features a chloromethyl group at position 2 and a methyl group at position 4 on the quinazoline ring, contributing to its reactivity and potential utility as a building block in drug development. It is typically a solid at room temperature and may exhibit solubility in organic solvents. Its chemical structure makes it relevant in pharmaceutical research and industrial synthesis.

What are the main uses of 2-(Chloromethyl)-4-methylquinazoline (CAS: 109113-72-6)?

2-(Chloromethyl)-4-methylquinazoline (CAS: 109113-72-6) is primarily used as a pharmaceutical intermediate in the development of drugs targeting cancer and infectious diseases. Its unique functional groups enable it to be a key component in synthesizing compounds with antitumor properties. Additionally, it finds applications in organic synthesis research and may be used in the production of dyes or materials with specific chemical properties. The compound's versatility in chemical reactions supports its role in both academic and industrial settings.

Is 2-(Chloromethyl)-4-methylquinazoline (CAS: 109113-72-6) safe?

2-(Chloromethyl)-4-methylquinazoline (CAS: 109113-72-6) requires careful handling due to its potential toxicity. While specific safety data may vary, it is generally considered hazardous and should be used in well-ventilated areas with appropriate protective equipment, such as gloves and goggles. Safety standards emphasize avoiding skin contact, inhalation, and ingestion. Always consult safety data sheets (SDS) and follow OSHA guidelines to ensure safe use in laboratory and industrial environments.

How should 2-(Chloromethyl)-4-methylquinazoline (CAS: 109113-72-6) be stored?

2-(Chloromethyl)-4-methylquinazoline (CAS: 109113-72-6) should be stored in a cool, dry, and dark place to maintain stability. It is typically kept in airtight containers to prevent moisture absorption and exposure to air. Storage conditions should avoid temperatures above 25°C and high humidity. Additionally, it should be protected from light and incompatible substances. Proper storage ensures safety and prolongs the compound's shelf life for research or industrial use.