(7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid

Basic Information

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CAS Number

106562-32-7

Molecular Formula

C12H11NO4

Molecular Weight

233.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Cryst.

SMILES

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CC1=C(C(=O)OC2=C1C=CC(=C2)N)CC(=O)O

InChI

InChI=1S/C12H11NO4/c1-6-8-3-2-7(13)4-10(8)17-12(16)9(6)5-11(14)15/h2-4H,5,13H2,1H3,(H,14,15)

InChIKey

QEQDLKUMPUDNPG-UHFFFAOYSA-N

LogP

1.3107199999999999

Topological Polar Surface Area

93.52999999999999 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

388

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

对光及湿度敏感

Synonyms & References

English

AM806697
T70054
EN300-7412542
BP-28126
LS-14055
F05-0020
2H-1-Benzopyran-3-acetic acid, 7-amino-4-methyl-2-oxo-
DTXSID20147648
2-(7-amino-4-methyl-2-oxochromen-3-yl)acetic acid
MFCD00081051
106562-32-7
2-(7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid
7-Amino-4-methyl-3-coumarinylacetic acid, BioReagent, suitable for fluorescence, ~90% (HPLC)
7-Amino-4-methyl-3-coumarinylacetic acid(AMCA)
AMCA-H
FT-0642624
2H-1-Benzopyran-3-acetic acid
?AMCA
AKOS015893953
7-Amino-4-methylcoumarin-3-acetate
SCHEMBL72225
HY-D0025
1ST164196
CS-0009918
QEQDLKUMPUDNPG-UHFFFAOYSA-N
7-Amino-4-methyl-3-coumarinylacetic acid
AMCA acid
J-100002
LCZC366
A801463
7-Amino-4-methylcoumarin-3-acetic acid

MDL Number

MFCD00081051

Customs Code

2932209090

FAQ

What are the physical and chemical properties of (7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid (CAS: 106562-32-7)?

(7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid is a white crystalline solid with a molecular weight of approximately 236.2 g/mol. It has a solubility in water of about 30 mg/mL. Chemically, it is stable, but it can react with strong acids or bases to form corresponding salts. It is used in pharmaceutical applications and has good reactivity with other functional groups.

How is (7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid (CAS: 106562-32-7) typically synthesized?

(7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid can be synthesized through a multi-step process involving the synthesis of chromanone, subsequent condensation with an amino compound, and acetylation. Common catalysts include acids like trifluoroacetic acid, and the overall yield is typically around 70-80%.

What industries use (7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid (CAS: 106562-32-7)?

(7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It also finds applications in the polymer industry for the development of functional polymers and in the sensor industry for the production of chemical sensors.

What precautions should be taken when handling (7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid (CAS: 106562-32-7)?

When handling (7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid, wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up with caution, using appropriate absorbents. Always refer to the safety data sheet (SDS) for detailed safety information.