Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate | CAS No. 1052715-76-0
Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate
Basic Information
CAS Number
1052715-76-0
Molecular Formula
C18H26N2O5
Molecular Weight
350.42 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate
- benzyl (3R,4R)-4-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-1-carboxylate
- (3R,4R)-benzyl 3-(tert-butoxycarbonylamino)-4-hydrox
- (3R,4R)-benzyl 3-(tert-butoxycarbonylamino)-4-hydroxypiperidin-1-carboxylate
- (3R,4R)-BENZYL 3-(TERT-BUTOXYCARBONYLAMINO)-4-HYDROXYPIPERIDINE-1-CARBOXYLATE
- AK-38462
- ANW-59399
- CTK8B8143
- KB-250868
- SureCN4120261
- Trans-benzyl 3-((tert-butoxycarbonyl)amino)-4-hydroxypiperidine-1-carboxylate
- trans-(3S,4S)-benzyl 3-((tert-butoxycarbonyl)amino)-4-hydroxypiperidine-1-carboxylate
- benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxy-piperidine-1-carboxylate
- ZOHDMZDTYNCUBC-HUUCEWRRSA-N
- S10991
- trans(+/-)-benzyl 3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate
- SCHEMBL4120261
- DTXSID60705342
- Benzylrel-(3R,4R)-3-((tert-butoxycarbonyl)amino)-4-hydroxypiperidine-1-carboxylate
- Benzyl (3R,4R)-3-[(tert-butoxycarbonyl)amino]-4-hydroxypiperidine-1-carboxylate
- Benzyl rel-(3R,4R)-3-((tert-butoxycarbonyl)amino)-4-hydroxypiperidine-1-carboxylate
- trans (+/-)-benzyl 3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate
- CS-0362882
- Benzyl (3R,4R)-3-((tert-butoxycarbonyl)amino)-4-hydroxypiperidine-1-carboxylate
- 859854-67-4
- 1052715-76-0
MDL Number
MFCD13152269
FAQ
What are the physical and chemical properties of Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate (CAS: 1052715-76-0)?
Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate is a white crystalline solid. Its molecular weight is approximately 407.5 g/mol. The compound is slightly soluble in water but more soluble in organic solvents like methanol and acetone. It is reactive towards nucleophiles and bases, making it suitable for chemical modifications in synthetic reactions.
How is Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate (CAS: 1052715-76-0) typically synthesized?
Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate is synthesized via a multi-step process involving the amino protection of a piperidine ring, followed by esterification. Common synthetic approaches include the use of tert-butyloxycarbonyl (Boc) protection and benzyl ester formation. The reaction typically requires a suitable solvent like dichloromethane and is catalyzed by a Lewis acid or anhydride. The yield of this synthesis is generally around 70-80%.
What industries use Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate (CAS: 1052715-76-0)?
Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate is primarily used in pharmaceuticals and organic synthesis. It serves as a building block for the synthesis of various complex molecules, including drugs. This compound is also utilized in polymer chemistry for the modification of polymers, and in sensor technology for the development of specific chemical sensors.
What precautions should be taken when handling Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate (CAS: 1052715-76-0)?
When handling Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate, it is essential to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be handled by absorbent material and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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