(1S)-(+)-(10-Camphorsulfonyl)oxaziridine

Basic Information

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CAS Number

104322-63-6

Molecular Formula

C10H15NO3S

Molecular Weight

229.3 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

172-174 °C

Boiling Point

317.6℃ at 760 mmHg

Density

1.2486 (rough estimate)

Flash Point

145.9°C

Refractive Index

1.5060 (estimate)

Specific Rotation

45 º (c=2, chloroform)

SMILES

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CC1(C2CCC13CS(=O)(=O)N4C3(C2)O4)C

InChI

InChI=1S/C10H15NO3S/c1-8(2)7-3-4-9(8)6-15(12,13)11-10(9,5-7)14-11/h7H,3-6H2,1-2H3/t7-,9+,10+,11?/m1/s1

InChIKey

GBBJBUGPGFNISJ-YDQXZVTASA-N

LogP

1.0996000000000001

Topological Polar Surface Area

49.68 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

466

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(1S)-(+)-(10-Camphorsulfonyl)oxaziridine
(2R,8aS)-(Camphorylsulfonyl)oxaziridine
E?-thia-4-azatetracyclo[6.2.1.0?,?.0?,?]undecane-3,3-dione
SCHEMBL24776681
AKOS015920326
(1S)-(10-Camphorsulfonyl)oxaziridine
GBBJBUGPGFNISJ-YDQXZVTASA-N
(1S)-(+)-2,N-Epoxy-exo-10,2-bornanesultam
F19978
104322-63-6
(camphorylsul-fonyl)oxaziridine
(1S,6S,8R)-11,11-dimethyl-5-oxa-3lambda6-thia-4-azatetracyclo[6.2.1.0^{1,6}.0^{4,6}]undecane-3,3-dione
(+)-(2r,8as)-(camphorsulfonyl)oxaziridine
153221-24-0
CS-W008074
(S)-(+)-(CAMPHORYLSULFONYL)OXAZIRIDINE
camphor-sulfonyloxaziridine
(4AS,7R,8aS)-9,9-Dimethyltetrahydro-4H-4a,7-methanobenzo-[c][1,2]oxazireno[2,3-b]isothiazole 3,3-dioxide
(4aS,7R,8aS)-9,9-Dimethyltetrahydro-4H-4a,7-methanobenzo[c][1,2]oxazireno[2,3-b]isothiazole 3,3-dioxide
(1S,6S,8R)-11,11-dimethyl-5-oxa-3
EN300-6480222
(1S)-(+)-(Camphorylsulfonyl)oxaziridine
(2R,8aS)-(+)-(Camphorylsulfonyl)oxaziridine [Asymmetric Oxidizing Reagent]
(2R,8aS)-(+)-(Camphorylsulfonyl)oxaziridine
(+)-((CAMPHORYL)SULFONYL)OXAZIRIDINE
(+)-(2R,8aS)-(10-camphorylsulfonyl)oxaziridine
(+)-(2R,8aS)-(Camphorylsulfonyl)oxaziridine
(+)-(camphorsulfonyl)oxaziridine
(1S)-(+)-(10-CAMPHORSULFONYL) OXAZIRINE
(1S)-(+)-(10-CAMPHORSULPHONYL)OXAZIRIDINE
(2R,8aS)-(+)-(Camphorylsulfonyl)

MDL Number

MFCD21332910

Customs Code

2934999090

FAQ

What are the physical and chemical properties of (1S)-(+)-(10-Camphorsulfonyl)oxaziridine (CAS: 104322-63-6)?

(1S)-(+)-(10-Camphorsulfonyl)oxaziridine is a white crystalline solid with a molecular weight of approximately 274.33 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. This compound exhibits high reactivity towards nucleophiles due to its oxaziridine ring, making it an important reagent in organic synthesis.

How is (1S)-(+)-(10-Camphorsulfonyl)oxaziridine (CAS: 104322-63-6) typically synthesized?

(1S)-(+)-(10-Camphorsulfonyl)oxaziridine is usually synthesized by the reaction of camphorsulfonic acid with oxaziridine. This process involves the condensation of camphorsulfonic acid with an appropriate aldehyde or ketone under acidic conditions, followed by treatment with a reducing agent to form the oxaziridine ring. The reaction is typically carried out in the presence of a suitable catalyst to enhance the yield and selectivity.

What industries use (1S)-(+)-(10-Camphorsulfonyl)oxaziridine (CAS: 104322-63-6)?

(1S)-(+)-(10-Camphorsulfonyl)oxaziridine is primarily used in the pharmaceutical industry for the synthesis of biologically active compounds. It is also employed in the polymer industry for the modification of polymers and in the sensor technology sector for the development of chemical sensors. Additionally, it has applications in semiconductor manufacturing for photoresist materials.

What precautions should be taken when handling (1S)-(+)-(10-Camphorsulfonyl)oxaziridine (CAS: 104322-63-6)?

When handling (1S)-(+)-(10-Camphorsulfonyl)oxaziridine, it is crucial to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a laboratory coat. This compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be carefully cleaned up using appropriate absorbents and disposed of according to local regulations. Always consult the Material Safety Data Sheet (MSDS) for detailed safety guidelines.