tert-Butyl 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)sulfonyl)piperazine-1-carboxylate | CAS No. 1042917-53-2
tert-Butyl 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)sulfonyl)piperazine-1-carboxylate
Basic Information
CAS Number
1042917-53-2
Molecular Formula
C21H33BN2O6S
Molecular Weight
452.38 g/mol
AD
Chemical Classification
Basic Physical Properties
Safety Information
View Safety InformationHazard Statement
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- 4-(4-Boc-Piperazin-1-ylsulfonyl)phenylboronic acid pinacol ester
- tert-butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]sulfonylpiperazine-1-carboxylate
- tert-Butyl 4-{[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzene]sulfonyl}piperazine-1-carboxylate
- 2-{4-[((4-tert-butoxycarbonyl)piperazin-1-yl)sulfonyl]phenyl}-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
- C-2491
- tert-butyl 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)sulfonyl)piperazine-1-carboxylate
- 4-(4-BOC-PIPERAZIN-1-YLSULFONYL)PHENYLBORONIC ACID
- tert-Butyl 4-{[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzene]sulfonyl}piperazine-1-carboxylat
- tert-butyl 4-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonyl]piperazine-1-carboxylate
- CS-0058029
- 4-(4-BOC-PIPERAZIN-1-YLSULFONYL)PHENYLBORONIC ACID PINACOL ESTER
- DTXSID70725490
- A896252
- 1042917-53-2
- DB-205028
- SYBIHBXDDYAZBX-UHFFFAOYSA-N
- P11749
- tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonyl]piperazine-1-carboxylate
- MB13644
- tert-Butyl 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)sulfonyl)piperazine-1-carboxylate
- 4-(4-Boc-piperazin-1-ylsulfonyl)phenylboronicacidpinacolester
- tert-butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonyl]piperazine-1-carboxylate
- MFCD14702533
- AS-2798
- tert-Butyl4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)sulfonyl)piperazine-1-carboxylate
- AKOS022168291
- TERT-BUTYL 4-(4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYLSULFONYL)PIPERAZINE-1-CARBOXYLATE
- tert-butyl 4-{[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzene]sulfonyl}piperazine-1-carboxylate
- SCHEMBL3023685
MDL Number
MFCD14702533
FAQ
What are the physical and chemical properties of tert-Butyl 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)sulfonyl)piperazine-1-carboxylate (CAS: 1042917-53-2)?
This compound is a white solid with a crystalline form. Its molecular weight is approximately 508.51 g/mol. It is poorly soluble in water but soluble in organic solvents like DMF and DMSO. Chemically, it is stable under normal conditions but can react with strong acids or bases. It is a key intermediate in organic synthesis, particularly in boronate ester formation.
How is tert-Butyl 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)sulfonyl)piperazine-1-carboxylate (CAS: 1042917-53-2) typically synthesized?
This compound is typically synthesized via a coupling reaction between 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl sulfonyl chloride and tert-butyl piperazine-1-carboxylate. The reaction is catalyzed by a palladium compound and a base such as potassium carbonate. The yield is generally around 70-80%, and the selectivity is high for the desired product.
What industries use tert-Butyl 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)sulfonyl)piperazine-1-carboxylate (CAS: 1042917-53-2)?
This compound is primarily used in the pharmaceutical industry as an intermediate in the synthesis of drugs. It is also utilized in the polymer industry for the modification of polymers, and in the semiconductor industry for the development of photoresists and other materials.
What precautions should be taken when handling tert-Butyl 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)sulfonyl)piperazine-1-carboxylate (CAS: 1042917-53-2)?
Proper personal protective equipment (PPE) such as gloves, goggles, and lab coat should be worn when handling this compound. It should be stored in a cool, dry place away from heat and direct sunlight. In case of spill, it should be cleaned up using appropriate absorbent materials. Handling should be done in a fume hood to minimize exposure. Always refer to the Safety Data Sheet (SDS) for comprehensive safety information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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