Diethyl (ethoxymethyl)phosphonate

Basic Information

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CAS Number

10419-80-4

Molecular Formula

C7H17O4P

Molecular Weight

196.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Agricultural Chemicals Pesticides Insecticides

Basic Physical Properties

Boiling Point

103°C/10mmHg

SMILES

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CCOCP(=O)(OCC)OCC

InChI

InChI=1S/C7H17O4P/c1-4-9-7-12(8,10-5-2)11-6-3/h4-7H2,1-3H3

InChIKey

PELDURRTQRGRMV-UHFFFAOYSA-N

LogP

2.2465

Topological Polar Surface Area

44.760000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

138

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

Phosphonic acid, (ethoxymethyl)-, diethyl ester
Diethyl (Ethoxymethyl)phosphonate
1-(diethoxyphosphorylmethoxy)ethane
Aethoxymethyl-phosphonsaeure-diaethylester
diethyl ethoxymethylphosphonate
ethoxymethyl-phosphonic acid diethyl ester
Ethoxymethyl-phosphonsaeure-diethylester
(Ethoxymethyl)phosphonic Acid Diethyl Ester
D5095
AKOS037646220
Diethyl (ethoxymethyl)phosphonate
DTXSID60520370
AS-67371
Diethyl(ethoxymethyl)phosphonate
MFCD00137939
SCHEMBL7940743
10419-80-4
D90365
(Ethoxymethyl)phosphonic acid diethyl ester

MDL Number

MFCD00137939

FAQ

What are the physical and chemical properties of Diethyl (ethoxymethyl)phosphonate (CAS: 10419-80-4)?

Diethyl (ethoxymethyl)phosphonate (CAS: 10419-80-4) is a colorless liquid with a molecular weight of approximately 168.22 g/mol. It has a specific gravity of 1.079 g/cm³ and a boiling point of 137-138°C. It is poorly soluble in water but readily soluble in ethanol and acetone. It is moderately reactive, particularly in the presence of acids or bases, and can undergo hydrolysis to form phosphoric acid derivatives.

How is Diethyl (ethoxymethyl)phosphonate (CAS: 10419-80-4) typically synthesized?

Diethyl (ethoxymethyl)phosphonate (CAS: 10419-80-4) is typically synthesized through the phosphonylation of ethoxymethyl ether using phosphorus oxychloride or phosphorus pentoxide in the presence of a suitable solvent. The reaction is performed under anhydrous conditions to improve yield and selectivity. Common solvents include chloroform or dichloromethane.

What industries use Diethyl (ethoxymethyl)phosphonate (CAS: 10419-80-4)?

Diethyl (ethoxymethyl)phosphonate (CAS: 10419-80-4) is used in various industries, including pharmaceuticals for certain intermediates and active pharmaceutical ingredients, and in the synthesis of organophosphorus compounds. It is also utilized in the development of sensors and as a reagent in analytical chemistry for specific applications.

What precautions should be taken when handling Diethyl (ethoxymethyl)phosphonate (CAS: 10419-80-4)?

When handling Diethyl (ethoxymethyl)phosphonate (CAS: 10419-80-4), it is important to use appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up immediately with appropriate materials; avoid inhalation of the vapor and do not allow the material to come into contact with water. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.