2,6-Dichloro-4-phenylquinoline

Basic Information

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CAS Number

10352-30-4

Molecular Formula

C15H9Cl2N

Molecular Weight

274.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1=CC=C(C=C1)C2=CC(=NC3=C2C=C(C=C3)Cl)Cl

InChI

InChI=1S/C15H9Cl2N/c16-11-6-7-14-13(8-11)12(9-15(17)18-14)10-4-2-1-3-5-10/h1-9H

InChIKey

FSVNVFMEUXPATP-UHFFFAOYSA-N

LogP

5.208600000000002

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

278

Synonyms & References

English

Quinoline, 2,6-dichloro-4-phenyl-
2,6-Dichloro-4-phenylquinoline
2,6-dichloro-4-phenylquinoline
HMS1474O13
SB70587
NCGC00172633-01
EU-0001018
Z207210374
EN300-88883
FSVNVFMEUXPATP-UHFFFAOYSA-N
SR-01000395981-1
ChemDiv3_000673
DTXSID70401944
10352-30-4
SR-01000395981
SCHEMBL11826284
AKOS001276597
F0016-0970
BRD-K76137601-001-01-5
G37879

MDL Number

MFCD00436567

FAQ

What are the physical and chemical properties of 2,6-Dichloro-4-phenylquinoline (CAS: 10352-30-4)?

2,6-Dichloro-4-phenylquinoline is a crystalline solid with a molecular weight of approximately 265.06 g/mol. It has low water solubility and high solubility in organic solvents such as acetone and dimethylformamide. It is slightly reactive, particularly towards strong bases and can form complexes with certain metal ions. Its stability under normal conditions makes it suitable for laboratory applications.

How is 2,6-Dichloro-4-phenylquinoline (CAS: 10352-30-4) typically synthesized?

2,6-Dichloro-4-phenylquinoline is typically synthesized via the condensation of 2,6-dichloroquinoline with phenylmagnesium bromide. The reaction requires use of anhydrous conditions and is catalyzed by tin(II) chloride. The yield is around 70-80%, and the product is purified by recrystallization from ethanol or acetone.

What industries use 2,6-Dichloro-4-phenylquinoline (CAS: 10352-30-4)?

2,6-Dichloro-4-phenylquinoline is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in organic semiconductor materials for electronic devices. Its properties make it useful in sensor technology and as a precursor in polymer chemistry.

What precautions should be taken when handling 2,6-Dichloro-4-phenylquinoline (CAS: 10352-30-4)?

When handling 2,6-Dichloro-4-phenylquinoline, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood. In case of spills, avoid direct contact and clean up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.