Compound Q&A
How is 2,6-Dichloro-4-phenylquinoline (CAS: 10352-30-4) typically synthesized?
Answer
2,6-Dichloro-4-phenylquinoline is typically synthesized via the condensation of 2,6-dichloroquinoline with phenylmagnesium bromide. The reaction requires use of anhydrous conditions and is catalyzed by tin(II) chloride. The yield is around 70-80%, and the product is purified by recrystallization from ethanol or acetone.
About
CAS No
10352-30-4
English Name
2,6-Dichloro-4-phenylquinoline
Molecular Formula
C15H9Cl2N
Molecular Weight
274.15 g/mol
SMILES
C1=CC=C(C=C1)C2=CC(=NC3=C2C=C(C=C3)Cl)Cl
InChIKey
FSVNVFMEUXPATP-UHFFFAOYSA-N
Last Updated: 2026-03-28 13:47
