Phyllanthin | CAS No. 10351-88-9

Phyllanthin

Basic Information

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CAS Number

10351-88-9

Molecular Formula

C24H34O6

Molecular Weight

418.53 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Physical State

Powder

Melting Point

96 ºC

Boiling Point

530.6°Cat760mmHg

Flash Point

207.3°C

Solubility

N/A

Refractive Index

1.516

Vapor Pressure

0.0±1.3 mmHg at 25°C

SMILES

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COCC(CC1=CC(=C(C=C1)OC)OC)C(CC2=CC(=C(C=C2)OC)OC)COC

InChI

InChI=1S/C24H34O6/c1-25-15-19(11-17-7-9-21(27-3)23(13-17)29-5)20(16-26-2)12-18-8-10-22(28-4)24(14-18)30-6/h7-10,13-14,19-20H,11-12,15-16H2,1-6H3/t19-,20-/m1/s1

InChIKey

KFLQGJQSLUYUBF-WOJBJXKFSA-N

LogP

4.031400000000003

Topological Polar Surface Area

55.38000000000001 Å²

Hydrogen Bond Donor/Acceptor

0 / 6

Complexity

407

Safety Information

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Storage Conditions

2-8℃

Synonyms & References

English

CHEBI:8177
PHYLLANTHIN (USP-RS)
DTXSID001319088
CHEMBL1253999
Benzene, 1,1'-(2,3-bis(methoxymethyl)-1,4-butanediyl)bis(3,4-dimethoxy-, (S-(R*,R*))-
A1-06840
PHYLLANTHIN (CONSTITUENT OF PHYLLANTHUS AMARUS)
AC1L7DK7
BUTANE, 1,4-DIMETHOXY-2,3-DIVERATRYL-, (2S,3S)-(+)-
NCI60_005684
NSC619043
Q27107847
Tetra-O-methylsecoisolariciresinol
HY-N4107
Phyllanthin
PHYLLANTHIN [USP-RS]
PHYLLANTHIN (CONSTITUENT OF PHYLLANTHUS AMARUS) [DSC]
UNII-75O1TFF47Z
CS-0032115
Phyllanthin, United States Pharmacopeia (USP) Reference Standard
AKOS032948449
MS-27324
NSC 619043
75O1TFF47Z
10351-88-9
4-[(2S,3S)-3-[(3,4-dimethoxyphenyl)methyl]-4-methoxy-2-(methoxymethyl)butyl]-1,2-dimethoxybenzene
Phyllanthin, analytical standard
3,3',4,4',9,9'-Hexamethoxylignan
4-[(2S,3S)-3-[(3,4-dimethoxyphenyl)methyl]-4-methoxy-2-(methoxymethyl)butyl]-1,2-dimethoxy-benzene
BENZENE, 1,1'-((2S,3S)-2,3-BIS(METHOXYMETHYL)-1,4-BUTANEDIYL)BIS(3,4-DIMETHOXY-
NSC-619043

MDL Number

MFCD17166965

Customs Code

2909309090

FAQ

What are the physical and chemical properties of Phyllanthin (CAS: 10351-88-9)?

Phyllanthin (CAS: 10351-88-9) is a crystalline compound with a molecular weight of approximately 267.23 g/mol. It is sparingly soluble in water but more soluble in organic solvents like methanol and ethanol. Phyllanthin is known to be relatively stable under normal conditions but can react with strong acids or bases. It has a characteristic UV absorption peak around 260 nm, which can be used for its detection and quantification.

How is Phyllanthin (CAS: 10351-88-9) typically synthesized?

Phyllanthin (CAS: 10351-88-9) can be synthesized through the total synthesis route involving multiple steps such as alkylation, acetylation, and deprotection. Commonly, the synthesis involves the use of acetic anhydride as a catalyst for acetylation. The overall yield is around 60-70%, and the synthetic route is selective towards the desired product, making it a feasible method for large-scale production.

What industries use Phyllanthin (CAS: 10351-88-9)?

Phyllanthin (CAS: 10351-88-9) is primarily used in the pharmaceutical industry for its potential as an antiviral and hepatoprotective agent. It is also explored in the natural product chemistry field for its biological activities. However, there are no significant applications in polymers, sensors, or semiconductors at present.

What precautions should be taken when handling Phyllanthin (CAS: 10351-88-9)?

Phyllanthin (CAS: 10351-88-9) should be handled with care due to its potential skin irritation and respiratory sensitization. Always wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize exposure. In case of a spill, immediately clean it up using appropriate absorbent materials and ensure proper disposal. Refer to the Safety Data Sheet (SDS) for detailed emergency procedures.