1-(4-Bromophenyl)-1-propanone

Basic Information

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CAS Number

10342-83-3

Molecular Formula

C9H9BrO

Molecular Weight

213.07 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

45.0 to 48.0 deg-C

Boiling Point

138°C/20mmHg

Refractive Index

1.5720 (estimate)

SMILES

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CCC(=O)C1=CC=C(C=C1)Br

InChI

InChI=1S/C9H9BrO/c1-2-9(11)7-3-5-8(10)6-4-7/h3-6H,2H2,1H3

InChIKey

UOMOSYFPKGQIKI-UHFFFAOYSA-N

LogP

3.041800000000002

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

137

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

4'-Bromopropiophenone, 99%
W-108851
EINECS 233-745-7
1-bromo-4-propionylbenzene
B1887
AH-034/32461042
InChI=1/C9H9BrO/c1-2-9(11)7-3-5-8(10)6-4-7/h3-6H,2H2,1H3
NSC 83574
4'-Bromopropiophenone
1-(4-bromophenyl)propan-1-one
DTXSID10145830
1-(4-bromophenyl)-propan-1-one
AS-11915
Q63395275
1-(4-Bromophenyl)-1-propanone #
CS-W014980
SY001608
Z104485724
4 inverted exclamation mark -Bromopropiophenone
UOMOSYFPKGQIKI-UHFFFAOYSA-
Propiophenone, 4'-bromo-
MFCD00000106
Q8EVM78HH6
SCHEMBL301100
NS00023230
10342-83-3
4-BROMOPHENYL ETHYL KETONE
4-bromopropio-phenone
4-Bromopropiophenone
1-[4-Bromophenyl]propan-1-one
4'-bromopropiophenon

MDL Number

MFCD00000106

Customs Code

2914399090

FAQ

What are the physical and chemical properties of 1-(4-Bromophenyl)-1-propanone (CAS: 10342-83-3)?

1-(4-Bromophenyl)-1-propanone is a colorless to yellowish liquid with a molecular weight of 236.01 g/mol. It is slightly soluble in water but miscible with common organic solvents such as ethanol, acetone, and toluene. Chemically, it is less reactive under normal conditions but can undergo nucleophilic substitution reactions. It has a high boiling point of 260°C and a melting point of -48°C.

How is 1-(4-Bromophenyl)-1-propanone (CAS: 10342-83-3) typically synthesized?

1-(4-Bromophenyl)-1-propanone can be synthesized through a bromination reaction of acetophenone with bromine in the presence of a Lewis acid like aluminum bromide. The reaction is carried out under anhydrous conditions to minimize side reactions. The yield is typically around 70-80%, with high selectivity towards the desired product.

What industries use 1-(4-Bromophenyl)-1-propanone (CAS: 10342-83-3)?

1-(4-Bromophenyl)-1-propanone is primarily used in the pharmaceutical and polymer industries. It serves as an intermediate in the synthesis of various drugs and also finds applications in the production of certain polymers. Its role in sensors and semiconductors is less common but still recognized in specific research areas.

What precautions should be taken when handling 1-(4-Bromophenyl)-1-propanone (CAS: 10342-83-3)?

Proper handling of 1-(4-Bromophenyl)-1-propanone requires wearing appropriate personal protective equipment (PPE), including gloves and safety goggles. It should be handled in a well-ventilated area or fume hood to avoid inhalation. In case of a spill, it should be cleaned up using appropriate absorbents, and the area should be flushed with water. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.