(2S)-3-(2,4-difluorophenyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid | CAS No. 1032337-49-7
(2S)-3-(2,4-difluorophenyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
Basic Information
CAS Number
1032337-49-7
Molecular Formula
C24H19F2NO4
Molecular Weight
423.42 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- FMOC-2,4-DIFLUORO-L-PHENYLALANINE
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,4-difluorophenyl)propanoic acid
- Fmoc-L-2,4-difluorophenylalanine (Fmoc-L-Phe(2,4-diF)-OH)
- (2S)-3-(2,4-difluorophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
- CS-0150075
- 1032337-49-7
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,4-difluorophenyl)propanoicacid
- Fmoc-L-2,4-Difluorophe
- EN300-3412079
- MFCD07371998
- Fmoc-L-(2,4-difluoro)phenylalanine
- A896575
- 4-(2-cyanobenzyl)pyrrolidine-3-carboxylic acid.HCl
- AS-32343
- (2S)-3-(2,4-difluorophenyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
- AKOS015948923
- FMOC-L-2,4-DIFLUOROPHENYLALANINE
- FMoc-L-2,4-Difluoro-Phenylpropionic acid
- 4-(2-cyanobenzyl)pyrrolidine-3-carboxylic acid·HCl
- (9H-Fluoren-9-yl)MethOxy]Carbonyl L-2,4-Difluorophe
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,4-difluoro-L-phenylalanine
- FMoc-L-2,4-difluorophe
- (S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(2,4-difluorophenyl)propanoic acid
MDL Number
MFCD07371998
FAQ
What are the physical and chemical properties of (2S)-3-(2,4-difluorophenyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid (CAS: 1032337-49-7)?
This compound is typically crystalline with a molecular weight of approximately 437.45 g/mol. It has limited water solubility, around 0.05 g/L at 25°C. It exhibits moderate reactivity, particularly towards nucleophilic substitution reactions. The compound is stable under neutral conditions but may degrade under acidic or basic conditions.
How is (2S)-3-(2,4-difluorophenyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid (CAS: 1032337-49-7) typically synthesized?
The compound is usually synthesized via multistep reactions involving protection of the amino group, coupling of the fluorenylmethoxy carbonyl group, and deprotection. Commonly used reagents include fluorenylmethanol, di-tert-butyl dicarbonate, and TFA (trifluoroacetic acid). The synthesis requires careful control of reaction conditions to achieve high yields and selectivity.
What industries use (2S)-3-(2,4-difluorophenyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid (CAS: 1032337-49-7)?
This compound is primarily used in the pharmaceutical industry for the synthesis of complex organic molecules and in the semiconductor industry for the production of photoresists. Its use in polymer and sensor applications is also growing due to its unique chemical properties.
What precautions should be taken when handling (2S)-3-(2,4-difluorophenyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid (CAS: 1032337-49-7)?
Handling this compound requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and followed by thorough rinsing of the area. Safety data sheets (SDS) should be consulted for detailed handling and storage instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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