(2S)-3-(2,4-difluorophenyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid(CAS: 1032337-49-7)

This compound is typically crystalline with a molecular weight of approximately 437.45 g/mol. It has limited water solubility, around 0.05 g/L at 25°C. It exhibits moderate reactivity, particularly towards nucleophilic substitution reactions. The compound is stable under neutral conditions but may degrade under acidic or basic conditions.

The compound is usually synthesized via multistep reactions involving protection of the amino group, coupling of the fluorenylmethoxy carbonyl group, and deprotection. Commonly used reagents include fluorenylmethanol, di-tert-butyl dicarbonate, and TFA (trifluoroacetic acid). The synthesis requires careful control of reaction conditions to achieve high yields and selectivity.

This compound is primarily used in the pharmaceutical industry for the synthesis of complex organic molecules and in the semiconductor industry for the production of photoresists. Its use in polymer and sensor applications is also growing due to its unique chemical properties.

Handling this compound requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and followed by thorough rinsing of the area. Safety data sheets (SDS) should be consulted for detailed handling and storage instructions.